Evidence map›Paper›PMID 29875175›Full record

ArticleBioscience reports2018

Structural and immunological characterization of

Ravi P N Mishra, Ravi S P Yadav, Christopher Jones, Salvatore Nocadello, George Minasov, Ludmilla A Shuvalova, Wayne F Anderson, Akshay Goel

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
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  7. Review
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  9. Review
  10. Article
  11. Monomeric crystal structure of the vaccine carrier protein CRMActa crystallographica. Section F, Structural biology communications · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ravi P N MishraBiological E. Limited, Genome Valley, MN Park, Shameerpet, Hyderabad 500078, India.
Ravi S P YadavBiological E. Limited, Genome Valley, MN Park, Shameerpet, Hyderabad 500078, India.
Christopher JonesNational Institute for Biological Standards and Control (NIBSC), Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, U.K.
Salvatore NocadelloCenter for Structural Genomics of Infectious Diseases, Northwestern University, Feinberg School of Medicine, Morton Bld. # 7-614 303 E. Chicago Ave., Chicago, IL 60611, U.S.A.
George MinasovCenter for Structural Genomics of Infectious Diseases, Northwestern University, Feinberg School of Medicine, Morton Bld. # 7-614 303 E. Chicago Ave., Chicago, IL 60611, U.S.A.
Ludmilla A ShuvalovaCenter for Structural Genomics of Infectious Diseases, Northwestern University, Feinberg School of Medicine, Morton Bld. # 7-614 303 E. Chicago Ave., Chicago, IL 60611, U.S.A.
Wayne F AndersonCenter for Structural Genomics of Infectious Diseases, Northwestern University, Feinberg School of Medicine, Morton Bld. # 7-614 303 E. Chicago Ave., Chicago, IL 60611, U.S.A.
Akshay GoelBiological E. Limited, Genome Valley, MN Park, Shameerpet, Hyderabad 500078, India akshay.goel@biologicale.co.in.
Biological E (India) · IN

Funding

NIAID NIH HHS HHSN272200700058CNIAID NIH HHS HHSN272201200026CNIAID NIH HHS HHSN272201700060C
6 · The paper itself

Abstract

It is established that the immunogenicity of polysaccharides is enhanced by coupling them to carrier proteins. Cross reacting material (CRM

Indexed as

Amino AcidsAnimalsBacterial ProteinsBlotting, WesternCrystallography, X-RayDrug CarriersEscherichia coliFemaleImmunoblottingMass SpectrometryMice, Inbred BALB CMolecular WeightPolysaccharidesRecombinant ProteinsTyphoid-Paratyphoid VaccinesVaccines, ConjugateAmino AcidsBacterial ProteinsCRM197 (non-toxic variant of diphtheria toxin)Drug CarriersPolysaccharidesRecombinant ProteinsTyphoid-Paratyphoid VaccinesVaccines, ConjugateCarrier ProteinConjugate VaccineCRM197E. coliX-ray crystallography

Identifiers

PMID29875175
PMCPMC6153374
OpenAlexW2806032090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.