Evidence map›Paper›PMID 29875146›Full record

ArticlemSphere2018

Metatranscriptome Analysis of the Vaginal Microbiota Reveals Potential Mechanisms for Protection against Metronidazole in Bacterial Vaginosis.

Zhi-Luo Deng, Cornelia Gottschick, Sabin Bhuju, Clarissa Masur, Christoph Abels, Irene Wagner-Döbler

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Probiotics for the Treatment of Bacterial Vaginosis: A Meta-Analysis.International journal of environmental research and public health · 2019
    Pooled it
  3. Observational
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  5. Review
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  12. Review
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  17. Article
  18. Review
  19. Review
  20. Vaginal Microbiome in Reproductive Medicine.Diagnostics (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhi-Luo Deng *Research Group Microbial Communication, Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany Zhiluo.Deng@helmholtz-hzi.de.
Cornelia Gottschick *Research Group Microbial Communication, Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Sabin BhujuGenome Analytics, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Clarissa MasurDr. August Wolff GmbH & Co. KG Arzneimittel, Bielefeld, Germany.
Christoph AbelsDr. August Wolff GmbH & Co. KG Arzneimittel, Bielefeld, Germany.
Irene Wagner-DöblerResearch Group Microbial Communication, Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Helmholtz Centre for Infection Research · DEDr. August Wolff (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial vaginosis (BV) is a prevalent multifactorial disease of women in their reproductive years characterized by a shift from the

Indexed as

Drug ToleranceAnti-Infective AgentsDNA RepairEndonucleasesFemaleGardnerella vaginalisGene Expression ProfilingHumansMetronidazoleMicrobiotaVaginaVaginosis, BacterialAnti-Infective AgentsEndonucleasesMetronidazoleantibiotic resistancebacterial vaginosismetatranscriptomevaginal microbiota

Identifiers

PMID29875146
PMCPMC5990888
OpenAlexW2953160311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.