ReviewEuropean respiratory review : an official journal of the European Respiratory Society2018
COPD stands for complex obstructive pulmonary disease.
Review in European respiratory review : an official journal of the European Respiratory Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04281316 (Impact of Nasal High Flow), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Nasal High Flow (NHF) Versus Home Non-invasive Ventilation (NIV) on Nocturnal Transcutaneous PCO2 (PtCO2) in Stable COPD Patients: A Non-inferiority Study
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sarcopenia in COPD: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2019Pooled it
- Real-Life Characteristics of Patients with COPD and Discordant CAT-mMRC Questionnaires.Journal of clinical medicine · 2025Article
- Treatable Traits in Patients with Obstructive Lung Diseases in a Well-Established Asthma/COPD Service for Primary Care.International journal of chronic obstructive pulmonary disease · 2025Article
- The Role of Diaphragmatic Ultrasound in Identifying Sarcopenia in COPD Patients: A Cross-Sectional Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Lipolysis engages CD36 to promote ZBP1-mediated necroptosis-impairing lung regeneration in COPD.Cell reports. Medicine · 2024Article
- Cellular and Molecular Biology of Mitochondria in Chronic Obstructive Pulmonary Disease.International journal of molecular sciences · 2024Review
- Symptom burden and its associations with clinical characteristics in patients with COPD: a clustering approach.ERJ open research · 2024Article
- Association of dietary inflammatory indices with sarcopenia and all-cause mortality in COPD patients.Frontiers in nutrition · 2024Article
- The Influence of Social Support in PROMs of Patients with COPD in Primary Care: A Scoping Review.Healthcare (Basel, Switzerland) · 2023Article
- Nonpharmacological management of psychological distress in people with COPD.European respiratory review : an official journal of the European Respiratory Society · 2023Review
- Perspectives and Attitudes of General Practitioners Towards Pharmacological and Non-Pharmacological COPD Management in a Belgian Primary Care Setting: A Qualitative Study.International journal of chronic obstructive pulmonary disease · 2023Article
- Acute effects of NIV on peripheral muscle function and aerobic performance in patients with chronic obstructive pulmonary disease: a pilot study.BMC pulmonary medicine · 2022Article
- Effects of Cigarette Smoke on Adipose and Skeletal Muscle Tissue: In Vivo and In Vitro Studies.Cells · 2022Article
- Multidimensional outcome assessment of pulmonary rehabilitation in traits-based clusters of COPD patients.PloS one · 2022Observational
- Hand Grip Strength and Likelihood of Moderate-to-Severe Airflow Limitation in the General Population.International journal of chronic obstructive pulmonary disease · 2022Article
- Circulating Extracellular Vesicles Are Associated with Disease Severity and Interleukin-6 Levels in COPD: A Pilot Study.Journal of clinical medicine · 2021Article
- Association between frailty index, lung function, and major clinical determinants in chronic obstructive pulmonary disease.Aging clinical and experimental research · 2021Article
- The narrative review of chronic obstructive pulmonary disease management in Turkey: medical treatment, pulmonary rehabilitation and endobronchial volume reduction.Journal of thoracic disease · 2021Review
- Treatable traits qualifying for nonpharmacological interventions in COPD patients upon first referral to a pulmonologist: the COPD sTRAITosphere.ERJ open research · 2020Article
- Profiling of Patients with COPD for Adequate Referral to Exercise-Based Care: The Dutch Model.Sports medicine (Auckland, N.Z.) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic obstructive pulmonary disease (COPD) has extensively been reported as a complex disease affecting patients' health beyond the lungs with a variety of intra- and extrapulmonary components and considerable variability between individuals. This review discusses the assessment of this complexity and underlines the importance of transdisciplinary management programmes addressing the physical, emotional and social health of the individual patient.COPD management is challenging and requires advanced, sophisticated strategies meeting the patient's individual needs. Due to the heterogeneity and complexity of the disease leading to non-linear and consequently poorly predictable treatment responses, multidimensional patient profiling is crucial to identify the right COPD patient for the right treatment. Current methods are often restricted to general, well-known and commonly used assessments neglecting potentially relevant (interactions between) individual, unique "traits" to finally ensure personalised treatment. Dynamic, personalised and holistic approaches are needed to tackle this multifaceted disease and to ensure personalised medicine and value-based healthcare.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.