Evidence map›Paper›PMID 29874846›Full record

ArticleMolecules (Basel, Switzerland)2018

Development of a Mouse Model of Prostate Cancer Using the Sleeping Beauty Transposon and Electroporation.

Hyun-Ji Choi, Han-Byul Lee, Sunyoung Jung, Hyun-Kyu Park, Woori Jo, Sung-Min Cho, Woo-Jin Kim, Woo-Chan Son

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Microfluidic Electroporation: Recent Advances and Applications.Advances in experimental medicine and biology · 2026
    Review
  2. Review
  3. Preclinical Imaging of Prostate Cancer.Seminars in nuclear medicine · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hyun-Ji ChoiAsan Institute for Life Sciences, Asan Medical Center, Songpa-gu, 05505 Seoul, Korea. snapple08@naver.com.
Han-Byul LeeAsan Institute for Life Sciences, Asan Medical Center, Songpa-gu, 05505 Seoul, Korea. onestar0620@naver.com.
Sunyoung JungAsan Institute for Life Sciences, Asan Medical Center, Songpa-gu, 05505 Seoul, Korea. flandus@naver.com.
Hyun-Kyu ParkAsan Institute for Life Sciences, Asan Medical Center, Songpa-gu, 05505 Seoul, Korea. nevok@hanmail.net.
Woori JoAsan Institute for Life Sciences, Asan Medical Center, Songpa-gu, 05505 Seoul, Korea. c2dar@hanmail.net.
Sung-Min ChoAsan Institute for Life Sciences, Asan Medical Center, Songpa-gu, 05505 Seoul, Korea. somnium14@naver.com.
Woo-Jin KimDepartment of Pathology, University of Ulsan College of Medicine, Songpa-gu, 05505 Seoul, Korea. woojinindi@naver.com.
Woo-Chan SonAsan Institute for Life Sciences, Asan Medical Center, Songpa-gu, 05505 Seoul, Korea. wcson32@hanmail.net.
Ulsan College · KRAsan Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Sleeping Beauty (SB) transposon system is non-viral and uses insertional mutagenesis, resulting in the permanent expression of transferred genes. Although the SB transposon is a useful method for establishing a mouse tumor model, there has been difficulty in using this method to generate tumors in the prostate. In the present study, electroporation was used to enhance the transfection efficiency of the SB transposon. To generate tumors, three constructs (a

Indexed as

DNA Transposable ElementsElectroporationAnimalsChromatography, High Pressure LiquidDisease Models, AnimalGene ExpressionMaleMice, Inbred C57BLMutagenesis, InsertionalProstatic NeoplasmsReal-Time Polymerase Chain ReactionDNA Transposable Elementsanimal modelselectroporationinsertional mutagenesisprostatic neoplasmsSleeping Beauty transposase

Identifiers

PMID29874846
PMCPMC6100630
OpenAlexW2806075351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.