Evidence map›Paper›PMID 29874821›Full record

ArticleViruses2018

1-Benzyl-3-cetyl-2-methylimidazolium Iodide (NH125) Is a Broad-Spectrum Inhibitor of Virus Entry with Lysosomotropic Features.

Sarah Moeschler, Samira Locher, Gert Zimmer

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sarah MoeschlerInstitut für Virologie und Immunologie (IVI), Abteilung Virologie, CH-3147 Mittelhäusern, Switzerland. sarah@moeschler.name.
Samira LocherInstitut für Virologie und Immunologie (IVI), Abteilung Virologie, CH-3147 Mittelhäusern, Switzerland. samira.locher@ivi.admin.ch.
Gert ZimmerInstitut für Virologie und Immunologie (IVI), Abteilung Virologie, CH-3147 Mittelhäusern, Switzerland. gert.zimmer@ivi.admin.ch.ORCID 0000-0002-2708-2507
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular kinases are crucial for the transcription/replication of many negative-strand RNA viruses and might serve as targets for antiviral therapy. In this study, a library comprising 80 kinase inhibitors was screened for antiviral activity against vesicular stomatitis virus (VSV), a prototype member of the family

Indexed as

AnimalsAntiviral AgentsChlorocebus aethiopsEbolavirusHeLa CellsHumansImidazolesInfluenza A Virus, H5N1 SubtypeLassa virusVero CellsVesiculovirusVirus InternalizationAntiviral AgentsImidazolesNH 125alkylated imidazoliumenveloped viruseukaryotic elongation factor 2 kinaseionic liquidkinase inhibitorlysosomotropic agentmembrane fusionvirus entry

Identifiers

PMID29874821
PMCPMC6024324
OpenAlexW2805783380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.