Evidence map›Paper›PMID 29874810›Full record

ReviewMaterials (Basel, Switzerland)2018

Scanning Kelvin Probe Microscopy: Challenges and Perspectives towards Increased Application on Biomaterials and Biological Samples.

Marco Salerno, Silvia Dante

Open access · goldAbstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Article
  3. Electric Field Cycling of Physisorbed Antibodies Reduces Biolayer Polarization Dispersion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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  10. Developments and Ongoing Challenges for Analysis of Surface-Bound Proteins.Annual review of analytical chemistry (Palo Alto, Calif.) · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marco SalernoMaterials Characterization Facility, Istituto Italiano di Tecnologia, via Morego 30, 16163 Genova, Italy. marco.salerno@iit.it.ORCID 0000-0003-4522-828X
Silvia DanteDepartment of Nanoscopy & NIC, Istituto Italiano di Tecnologia, via Morego 30, 16163 Genova, Italy. silvia.dante@iit.it.ORCID 0000-0001-6906-8482
Italian Institute of Technology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report and comment on the possible increase of application of scanning Kelvin probe microscopy (SKPM) for biomaterials, biological substrates, and biological samples. First, the fundamental concepts and the practical limitations of SKPM are presented, pointing out the difficulties in proper probe calibration. Then, the most relevant literature on the use of SKPM on biological substrates and samples is briefly reviewed. We report first about biocompatible surfaces used as substrates for subsequent biological applications, such as cultures of living cells. Then, we briefly review the SKPM measurements made on proteins, DNA, and similar biomolecular systems. Finally, some considerations about the perspectives for the use of SKPM in the field of life sciences are made. This work does not pretend to provide a comprehensive view of this emerging scenario, yet we believe that it is time to put these types of application of SKPM under focus, and to face the related challenges, such as measuring in liquid and quantitative comparison with other techniques for the electrical potential readout.

Indexed as

biomaterialsbiomoleculeselectrical cuesliving cells substratessurface potential

Identifiers

PMID29874810
PMCPMC6025522
OpenAlexW2807225573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.