Evidence map›Paper›PMID 29874689›Full record

Trial reportThrombosis and haemostasis2018

Pharmacodynamic Effects of a 6-Hour Regimen of Enoxaparin in Patients Undergoing Primary Percutaneous Coronary Intervention (PENNY PCI Study).

Wael Sumaya, William A E Parker, Rebekah Fretwell, Ian R Hall, David S Barmby, James D Richardson, Javaid Iqbal, Zulfiquar Adam, Kenneth P Morgan, Julian P Gunn and 5 more

Registry-linked trialOpen access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Thrombosis and haemostasis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03568838 (Prolonged Enoxaparin in Primary Percutaneous Coronary Intervention Compared With Standard of Care Therapy - The PENNYWISE Feasibility Study), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03568838 phase4completednot on this map

Prolonged Enoxaparin in Primary Percutaneous Coronary Intervention Compared With Standard of Care Therapy - The PENNYWISE Feasibility Study

TypeinterventionalSponsorSheffield Teaching Hospitals NHS Foundation TrustRan2018 to 2020Enrolled100ConditionsMyocardial InfarctionArmsEnoxaparin
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. New Antithrombotic Drugs in Acute Coronary Syndrome.Journal of clinical medicine · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Wael SumayaDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
William A E ParkerDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
Rebekah FretwellDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
Ian R HallDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
David S BarmbyDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
James D RichardsonDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
Javaid IqbalDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
Zulfiquar AdamDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
Kenneth P MorganDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
Julian P GunnDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
Annah E MasonDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
Heather M JudgeDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
Christopher P GaleLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.
Ramzi A AjjanLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.
Robert F StoreyDepartment of Infection, Immunity and Cardiovascular Disease, Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
Sheffield Teaching Hospitals NHS Foundation Trust · GBNorthern General Hospital · GBUniversity of Sheffield · GBUniversity of Leeds · GB

Funding

British Heart Foundation FS/15/82/31824
6 · The paper itself

Abstract

Delayed onset of action of oral P2Y

Indexed as

Percutaneous Coronary InterventionAgedAnalgesics, OpioidAnticoagulantsBlood CoagulationCoronary ThrombosisDrug Administration ScheduleDrug MonitoringEnglandEnoxaparinFemaleFibrinolytic AgentsHumansInfusions, IntravenousMaleMiddle AgedAnalgesics, OpioidAnticoagulantsEnoxaparinFibrinolytic AgentsPlatelet Aggregation InhibitorsPurinergic P2Y Receptor Antagonists

Identifiers

PMID29874689
PMCPMC6202933
OpenAlexW2806058188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.