Evidence map›Paper›PMID 29874685›Full record

GuidelineRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2018

Guidelines for HPV-DNA Testing for Cervical Cancer Screening in Brazil.

Luiz Carlos Zeferino, Joana Bragança Bastos, Diama Bhadra Andrade Peixoto do Vale, Rita Maria Zanine, Yara Lucia Mendes Furtado de Melo, Walquíria Quida Salles Pereira Primo, Flávia de Miranda Corrêa, Isabel Cristina Chulvis do Val, Fábio Russomano

Open access · diamondAbstract readPractice Guideline
In one paragraph

Guideline in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Human papillomavirus infection and screening strategies.World journal of clinical oncology · 2025
    Review
  4. Gastrin-releasing peptide receptor: a promising new biomarker to identify cervical precursor lesions and cancer.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Cervical Cancer Screening with HPV Testing: Updates on the Recommendation.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Article
  12. Article
  13. HPV infection - Screening, diagnosis and management of HPV-induced lesions.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2021
    Article
  14. Article
  15. Article
  16. Comments on: Limitations of HPV DNA Testing in Screening of Cervical Adenocarcinomas.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2019
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Luiz Carlos ZeferinoFaculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.
Joana Bragança BastosFaculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.
Diama Bhadra Andrade Peixoto do ValeFaculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.
Rita Maria ZanineUniversidade Federal do Paraná, Curitiba, Paraná, Brazil.
Yara Lucia Mendes Furtado de MeloUniversidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Walquíria Quida Salles Pereira PrimoUniversidade de Brasília, Brasília, Distrito Federal, Brazil.
Flávia de Miranda CorrêaInstituto Nacional de Câncer José Alencar Gomes da Silva, Rio de Janeiro, Rio de Janeiro, Brazil.
Isabel Cristina Chulvis do ValUniversidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil.
Fábio RussomanoInstituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, da Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRFundação Oswaldo Cruz · BRInstituto Nacional do Câncer · BRUniversidade de Brasília · BRUniversidade Federal do Paraná · BRUniversidade Federal do Rio de Janeiro · BRUniversidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence-based clinical guidelines ensure best practice protocols are available in health care. There is a widespread use of human papillomavirus deoxyribonucleic acid (HPV-DNA) tests in Brazil, regardless of the lack of official guidelines. On behalf of the Brazilian Association for the Lower Genital Tract Pathology and Colposcopy (ABPTGIC, in the Portuguese acronym), a team of reviewers searched for published evidence and developed a set of recommendations for the use of HPV-DNA tests in cervical cancer screening in Brazil. The product of this process was debated and consensus was sought by the participants. One concern of the authors was the inclusion of these tests in the assessment of women with cytologic atypia and women treated for cervical intraepithelial neoplasia (CIN). Testing for HPV is recommended in an organized screening scenario to identify women with precursor lesions or asymptomatic cervical cancer older than 30 years of age, and it can be performed every 5 years. It also has value after the cytology showing atypical squamous cells of undetermined significance (ASC-US) or low-grade squamous intraepithelial lesions (LSILs) as a triage test for colposcopy, in the investigation of other cytological alterations when no abnormal findings are observed at colposcopy, seeking to exclude disease, or, further, after treatment of high-grade cervical intraepithelial neoplasia, to rule out residual disease.

Indexed as

BrazilEarly Detection of CancerFemaleHuman Papillomavirus DNA TestsHumansPapillomavirus InfectionsUterine Cervical Neoplasms

Identifiers

PMID29874685
PMCPMC10309354
OpenAlexW2805799490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.