Evidence map›Paper›PMID 29874548›Full record

ReviewThe international journal of biochemistry & cell biology2018

Spectroscopic analysis beyond the diffraction limit.

Biqin Dong, Janel L Davis, Cheng Sun, Hao F Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The international journal of biochemistry & cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Biqin DongDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA; Department of Mechanical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Janel L DavisDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Cheng SunDepartment of Mechanical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Hao F ZhangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA. Electronic address: hfzhang@northwestern.edu.
Northwestern University · US

Funding

Developing Capacity to Evaluate Training Programs via Development of Human, Institutional and Social CapitalT32GM008449 · NIGMS · NORTHWESTERN UNIVERSITY · PI LEONARD, JOSHUA NATHANIEL · 1993 to 2023
$7.8M
Investigating oxygen metabolism in diabetic retinopathyR01EY026078 · NEI · NORTHWESTERN UNIVERSITY · PI SHEIBANI, NADER, ZHANG, HAO F · 2016 to 2020
$2.3M
NEI NIH HHS R01 EY026078NIGMS NIH HHS T32 GM008449
6 · The paper itself

Abstract

The recent surge in spectroscopic Single-Molecule Localization Microscopy (sSMLM) offers exciting new capabilities for combining single molecule imaging and spectroscopic analysis. Through the synergistic integration of super-resolution optical microscopy and single-molecule spectroscopy, sSMLM offers combined strengths from both fields. By capturing the full spectra of single molecule fluorescent emissions, sSMLM can distinguish minute spectroscopic variations from individual fluorescent molecules while preserving nanoscopic spatial localization precision. It can significantly extend the coding space for multi-molecule super-resolution imaging. Furthermore, it has the potential to detect spectroscopic variations in fluorescence emission associated with molecular interactions, which further enables probing local chemical and biochemical inhomogeneities of the nano-environments. In this review, we seek to explain the working principle of sSMLM technologies and the status of sSMLM techniques towards new super-resolution imaging applications.

Indexed as

alpha-SynucleinAmyloid beta-PeptidesAnimalsChlorocebus aethiopsCOS CellsFluorescent DyesHumansHydrophobic and Hydrophilic InteractionsLipid BilayersMicroscopy, FluorescenceMolecular ImagingOxazinesRhodaminesSingle Molecule Imagingalpha-SynucleinAmyloid beta-PeptidesFluorescent DyesLipid Bilayersnile redOxazinesRhodaminesFluorescence spectral imagingSingle-molecule spectroscopySuper-resolution microscopy

Identifiers

PMID29874548
PMCPMC6635922
OpenAlexW2807529840

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.