ArticlePloS one2018
Video-fluoroscopic swallowing study scale for predicting aspiration pneumonia in Parkinson's disease.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A comprehensive review of the diagnosis and treatment of Parkinson's disease dysphagia and aspiration.Expert review of gastroenterology & hepatology · 2020Pooled it
- Artificial intelligence for dysphagia screening: A machine learning approach.PLOS digital health · 2026Article
- Consensus expert recommendations for management of dysphagia during hospital admission in Parkinson's disease.Journal of Parkinson's disease · 2026Review
- Swallowing impairment and aspiration risk in clinically stabilized patients hospitalized for acute respiratory events: a cohort-wide machine-learning analysis with COPD-specific insights.Frontiers in medicine · 2026Article
- Characteristics and Clinical Analysis of Dysphagia Caused by Pontine Infarction: A Video Fluoroscopic Swallowing Study.Brain and behavior · 2025Article
- Factors Related to Oropharyngeal Dysphagia in Adults in a Healthcare Center in Colombia.Healthcare (Basel, Switzerland) · 2025Article
- Evaluation of a Machine Learning-Based Dysphagia Prediction Tool in Clinical Routine: A Prospective Observational Cohort Study.Dysphagia · 2023Observational
- The Role of Aspiration Amount on Airway Protective Responses in People with Neurogenic Dysphagia.Dysphagia · 2023Article
- Clinical and Swallowing Characteristics Related With Respiratory Infection in Parkinsonism Patients.Annals of rehabilitation medicine · 2023Article
- Dysphagia and aspiration during a Parkinson's hospitalization: a care partner's perspective and recommendations for improving standards of care.Frontiers in aging neuroscience · 2023Article
- Clinical Usefulness of the Korean Version of the Dysphagia Handicap Index: Reliability, Validity, and Role as a Screening Test.Dysphagia · 2022Article
- Electromyographic measures of asymmetric muscle control of swallowing in Parkinson's disease.PloS one · 2022Article
- Unraveling the Mechanisms Underlying Irregularities in Inspiratory Rhythm Generation in a Mouse Model of Parkinson's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Diagnosis and treatment of neurogenic dysphagia - S1 guideline of the German Society of Neurology.Neurological research and practice · 2021Article
- Article
- Videofluoroscopic Swallowing Study Findings Associated With Subsequent Pneumonia in Patients With Dysphagia Due to Frailty.Frontiers in medicine · 2021Article
- Observational
- Impact of Residual Drug in the Pharynx on the Delayed-On Phenomenon in Parkinson's Disease Patients.Movement disorders clinical practice · 2020Article
- Management of Dysphagia in Patients with Parkinson's Disease and Related Disorders.Internal medicine (Tokyo, Japan) · 2020Review
- Non-pharmacological Treatment Challenges in Early Parkinson's Disease for Axial and Cognitive Symptoms: A Mini Review.Frontiers in neurology · 2020Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionA number of video-fluoroscopic swallowing study (VFSS) abnormalities have been reported in patients with Parkinson's disease (PD). However, the most crucial finding of subsequent aspiration pneumonia has not been validated fully. We conducted a retrospective and case-control study to determine the clinically significant VFSS findings in this population, and to propose a practical scale for predicting aspiration pneumonia in patients with PD.
methodsWe enrolled 184 PD patients who underwent VFSS because of suspected dysphagia. The patients who developed aspiration pneumonia within six months of the VFSS were assigned as cases and the patients without aspiration pneumonia at six months were designated as controls. Logistic regression analysis was performed to determine the prognostic VFSS features based on the data of swallowing 3 mL of jelly, which were used to make a PD VFSS scale (PDVFS). The validity of the new PDVFS was evaluated by ROC analysis. Additionally, we used the survival time analysis to compare time to death between groups, stratified by the PDVFS score.
resultsTwenty-five patients developed aspiration pneumonia. Among the previously-proposed VFSS features, mastication, lingual motility prior to transfer, aspiration, and total swallow time were identified as significant prognostic factors. We combined these factors to form the PDVFS. The PDVFS score ranges from 0 to 12, with 12 being the worst. ROC analysis revealed 92% sensitivity and 82% specificity at a cutoff point of 3. The higher PDVFS group showed shorter time-to-death than the lower PDVFS group (log rank P = 0.001).
conclusionOur newly developed VFSS severity scale (based on jelly swallowing) for patients with PD was easy to rate and could predict subsequent aspiration pneumonia and poor prognosis in patients with PD.
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