Evidence map›Paper›PMID 29874107›Full record

ArticleAmerican journal of physiology. Cell physiology2018

ZO-1 protein is required for hydrogen peroxide to increase MDCK cell paracellular permeability in an ERK 1/2-dependent manner.

Sahar Bilal, Shirin Jaggi, Danielle Janosevic, Nikita Shah, Shereen Teymour, Angelina Voronina, Jessica Watari, Josephine Axis, Kurt Amsler

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Epithelial Cell Leak Pathway.International journal of molecular sciences · 2021
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sahar BilalDepartment of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, New York.
Shirin JaggiDepartment of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, New York.
Danielle JanosevicDepartment of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, New York.
Nikita ShahDepartment of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, New York.
Shereen TeymourDepartment of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, New York.
Angelina VoroninaDepartment of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, New York.
Jessica WatariDepartment of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, New York.
Josephine AxisDepartment of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, New York.
Kurt AmslerDepartment of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, New York.
New York Institute of Technology · US

Funding

Src Family Kinases and Control of Epithelial Cell Paracellular PermeabilityR15DK091749 · NIDDK · NEW YORK INST OF TECHNOLOGY · PI AMSLER, KURT F · 2012 to 2012
$486k
NIDDK NIH HHS R15 DK091749
6 · The paper itself

Abstract

Hydrogen peroxide (H

Indexed as

Actin CytoskeletonActinsAdenosine TriphosphatasesAnimalsCarrier ProteinsCell LineCell Membrane PermeabilityDogsHydrogen PeroxideMadin Darby Canine Kidney CellsMAP Kinase Signaling SystemMyosinsOccludinStress FibersZonula Occludens-1 ProteinActinsAdenosine TriphosphatasesCarrier ProteinsHydrogen PeroxideMyosinsOccludinZonula Occludens-1 Proteinhydrogen peroxidepermeabilitytight junction

Identifiers

PMID29874107
PMCPMC6171043
OpenAlexW2805366216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.