ArticleACS nano2018
Metallic Nanoislands on Graphene for Monitoring Swallowing Activity in Head and Neck Cancer Patients.
Article in ACS nano, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 56 citations in OpenAlex.
- Wearable bioelectronics for cancer theranostics.Microsystems & nanoengineering · 2025Review
- Current Technological Advances in Dysphagia Screening: Systematic Scoping Review.Journal of medical Internet research · 2025Article
- Wearable Biodevices Based on Two-Dimensional Materials: From Flexible Sensors to Smart Integrated Systems.Nano-micro letters · 2025Review
- Multimodal deep ensemble classification system with wearable vibration sensor for detecting throat-related events.NPJ digital medicine · 2025Article
- Toward an AI Era: Advances in Electronic Skins.Chemical reviews · 2024Review
- Article
- Advancements and Challenges in Non-Invasive Sensor Technologies for Swallowing Assessment: A Review.Bioengineering (Basel, Switzerland) · 2024Review
- Article
- Soft Electronics for Health Monitoring Assisted by Machine Learning.Nano-micro letters · 2023Review
- Machine Learning-Enhanced Flexible Mechanical Sensing.Nano-micro letters · 2023Review
- Metallic Nanoislands on Graphene for Biomechanical Sensing.ACS omega · 2020Review
- Exploring the limits of sensitivity for strain gauges of graphene and hexagonal boron nitride decorated with metallic nanoislands.Nanoscale · 2020Article
- Combining High Sensitivity and Dynamic Range: Wearable Thin-Film Composite Strain Sensors of Graphene, Ultrathin Palladium, and PEDOT:PSS.ACS applied nano materials · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
There is a need to monitor patients with cancer of the head and neck postradiation therapy, as diminished swallowing activity can result in disuse atrophy and fibrosis of the swallowing muscles. This paper describes a flexible strain sensor comprising palladium nanoislands on single-layer graphene. These piezoresistive sensors were tested on 14 disease-free head and neck cancer patients with various levels of swallowing function: from nondysphagic to severely dysphagic. The patch-like devices detected differences in (1) the consistencies of food boluses when swallowed and (2) dysphagic and nondysphagic swallows. When surface electromyography (sEMG) is obtained simultaneously with strain data, it is also possible to differentiate swallowing vs nonswallowing events. The plots of resistance vs time are correlated to specific events recorded by video X-ray fluoroscopy. Finally, we developed a machine-learning algorithm to automate the identification of bolus type being swallowed by a healthy subject (86.4%. accuracy). The algorithm was also able to discriminate between swallows of the same bolus from either the healthy subject or a dysphagic patient (94.7% accuracy). Taken together, these results may lead to noninvasive and home-based systems for monitoring of swallowing function and improved quality of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.