ArticleBiomarkers in medicine2018
The validity, stability, and utility of measuring uric acid in saliva.
Article in Biomarkers in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 69 citations in OpenAlex.
- Salivary uric acid remote serial self-testing for prediction of adverse pregnancy outcomes of uteroplacental dysfunction.Acta obstetricia et gynecologica Scandinavica · 2026Observational
- Clinical Implications and Research Progress of Salivary Biomarkers for Endocrine and Metabolic Disorders.Diabetes, obesity & metabolism · 2026Review
- Salivary and Serum Analytes and Their Associations with Self-rated Health Among Healthy Young Adults.International journal of behavioral medicine · 2026Article
- Age and gender intersectionality among African Americans: Salivary uric acid is associated with shorter telomere length in younger adults and men.Psychoneuroendocrinology · 2025Article
- Effect of age and disease on saliva and serum biomarkers of stress, inflammation, immunity, redox and general health status in pigs.Scientific reports · 2025Article
- Exploring Salivary Biomarkers in Pediatric Obesity: A Scoping Review.International journal of molecular sciences · 2025Article
- Molecularly imprinted nanocomposites-based synthetic antibodies for uric acid-specific non-invasive electrochemical gout sensors.Mikrochimica acta · 2025Article
- Microbial functional pathways based on metatranscriptomic profiling enable effective saliva-based health assessments for precision wellness.Computational and structural biotechnology journal · 2024Article
- A sex-dependent salivary bacterium influences oral mucositis severity after allogeneic hematopoietic cell transplantation.NPJ biofilms and microbiomes · 2024Article
- The salivary metabolome of children and parental caregivers in a large-scale family environment study.npj metabolic health and disease · 2024Article
- Label-Free Metal-Oxide Transistor Biosensors for Metabolite Detection in Human Saliva.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
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- Salivary uric acid across child development and associations with weight, height, and body mass index.Frontiers in pediatrics · 2023Article
- The implications of socioeconomic factors on salivary bioscience methodological variables in a large pediatric multi-site study.Frontiers in public health · 2023Article
- Science of interdisciplinary salivary bioscience: history and future directions.Biomarkers in medicine · 2022Review
- Electrochemical detection of uric acid in undiluted human saliva using uricase paper integrated electrodes.Scientific reports · 2022Article
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- Characterizing and Evaluating Diurnal Salivary Uric Acid Across Pregnancy Among Healthy Women.Frontiers in endocrinology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
aimSerum uric acid (UA) is associated with many health conditions, including kidney, cardiovascular, and metabolic disorders. We examined the validity and stability of salivary UA as a noninvasive measure of serum UA. MATERIALS &
methodsUsing serum and salivary UA data from healthy adults (n = 99), we examined the UA serum-saliva correlation, and UA associations with adiponectin and C-reactive protein. Using longitudinal data from young adults (n = 182), we examined salivary UA stability.
resultsWe found robust positive serum-saliva correlations for UA. UA and adiponectin were inversely related in serum and saliva. Salivary UA was relatively stable; 62-66% of variance could be attributed to a latent trait-like component.
conclusionSalivary UA may be an important biomarker indexing health and disease risk.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.