Evidence map›Paper›PMID 29873292›Full record

ArticleJournal of neurotrauma2019

White Matter Correlates of Mild Traumatic Brain Injuries in Women Subjected to Intimate-Partner Violence: A Preliminary Study.

Eve M Valera, Aihua Cao, Ofer Pasternak, Martha E Shenton, Marek Kubicki, Nikos Makris, Noor Adra

Registry-linked trialAbstract read
In one paragraph

Article in Journal of neurotrauma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04890925 (Evaluating The Effectiveness Of A Community Support Network Intervention For), which is not on this map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04890925 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Evaluating The Effectiveness Of A Community Support Network Intervention For

TypeinterventionalSponsorUniversity of British ColumbiaRan2022 to 2024Enrolled78ConditionsMild Traumatic Brain InjuryArmsCommunity Support Network (CSN) intervention, Usual care
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eve M Valera1 Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.
Aihua Cao1 Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.
Ofer Pasternak3 Departments of Radiology and Psychiatry, Harvard Medical School, Boston, Massachusetts.
Martha E Shenton3 Departments of Radiology and Psychiatry, Harvard Medical School, Boston, Massachusetts.
Marek Kubicki2 Department of Psychiatry, Massachusetts General Hospital, Charlestown, Massachusetts.
Nikos Makris6 Departments of Radiology and Psychiatry, Harvard Medical School, Boston, Massachusetts.
Noor Adra1 Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLLAND, POLINA · 2012 to 2022
$20.9M
ULTRAHIGH FIELD TECHNOLOGY FOR FUNCTIONAL IMAGINGP41RR014075 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 1999 to 2011
$16.4M
Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
Neural substrates of diffusion imaging in cognitively aging rhesus monkeysR01AG042512 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI KUBICKI, MAREK, MAKRIS, NIKOLAOS · 2013 to 2023
$6.5M
High Resolution, Comprehensive Atlases of the Human Brain MorphologyR01MH112748 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI BOUIX, SYLVAIN, KUBICKI, MAREK · 2018 to 2022
$4.1M
Mechanisms of myelin damage and cognitive impairment in the aging monkey: Gene Expression, Neurophysiology, Inflammation and Effects of Calorie RestrictionRF1AG043640 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ROSENE, DOUGLAS L · 2019 to 2019
$3.7M
Histopathology, Neuroimaging and Mechanism of Myelin Damage in Aging Monkey BrainR01AG043640 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ROSENE, DOUGLAS L · 2013 to 2017
$3.0M
Diffusion Imaging Biomarkers for Risk, Onset and Outcome in SchizophreniaR01MH102377 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI KUBICKI, MAREK · 2014 to 2018
$2.8M
Patient-specific, Effective, and Rational Functional Connectivity Targeting for DBS in OCDR01MH111917 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI DOUGHERTY, DARIN D, MAKRIS, NIKOLAOS · 2017 to 2019
$2.1M
A Storage Area Network for Structural and Functional Image AnalysisS10RR023401 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2009 to 2009
$2.0M
SILICON GRAPHICS PRISM EXTREME 128P/1TBS10RR023043 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, ALMA GREGORY · 2006 to 2006
$1.5M
Mentoring and Neuroimaging Research on White Matter Pathology in SchizophreniaK24MH110807 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI KUBICKI, MAREK · 2017 to 2021
$945k
NCCIH NIH HHS R21 AT008865NCRR NIH HHS P41 RR014075NCRR NIH HHS S10 RR023043NCRR NIH HHS S10 RR023401NIA NIH HHS R01 AG042512NIA NIH HHS R01 AG043640NIA NIH HHS RF1 AG043640NIBIB NIH HHS P41 EB015896NIBIB NIH HHS P41 EB015902NIMH NIH HHS K24 MH110807NIMH NIH HHS R01 MH102377NIMH NIH HHS R01 MH111917NIMH NIH HHS R01 MH112748RRD VA I01 RX000928
6 · The paper itself

Abstract

A large proportion (range of 44-75%) of women who experience intimate-partner violence (IPV) have been shown to sustain repetitive mild traumatic brain injuries (mTBIs) from their abusers. Further, despite requests for research on TBI-related health outcomes, there are currently only a handful of studies addressing this issue and only one prior imaging study that has investigated the neural correlates of IPV-related TBIs. In response, we examined specific regions of white matter microstructure in 20 women with histories of IPV. Subjects were imaged on a 3-Tesla Siemens Magnetom TrioTim scanner using diffusion magnetic resonance imaging. We investigated the association between a score reflecting number and recency of IPV-related mTBIs and fractional anisotropy (FA) in the posterior and superior corona radiata as well as the posterior thalamic radiation, brain regions shown previously to be involved in mTBI. We also investigated the association between several cognitive measures, namely learning, memory, and cognitive flexibility, and FA in the white matter regions of interest. We report a negative correlation between the brain injury score and FA in regions of the posterior and superior corona radiata. We failed to find an association between our cognitive measures and FA in these regions, but the interpretation of these results remains inconclusive due to possible power issues. Overall, these data build upon the small but growing literature demonstrating potential consequences of mTBIs for women experiencing IPV, and further underscore the urgent need for larger and more comprehensive studies in this area.

Indexed as

Intimate Partner ViolenceAdultBrainBrain ConcussionCognitionDiffusion Tensor ImagingFemaleHumansMemoryNeuropsychological TestsWhite MatterYoung Adultcorona radiatadiffusion tensor imagingdomestic violenceintimate-partner violencemild traumatic brain injury

Identifiers

PMID29873292
PMCPMC6387564

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.