Evidence map›Paper›PMID 29873008›Full record

ArticleAdvances in therapy2018

Pooled Aquablation Results for American Men with Lower Urinary Tract Symptoms due to Benign Prostatic Hyperplasia in Large Prostates (60-150 cc).

Bilal Chughtai, Dominique Thomas

3 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Advances in therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02505919 nacompletednot on this map

A Prospective Multicenter Randomized Blinded Study Comparing Aquablation of the Prostate With the AQUABEAM System and TURP for the Treatment of LUTS

TypeinterventionalSponsorPROCEPT BioRoboticsRan2015 to 2021Enrolled184ConditionsBenign Prostatic Hyperplasia (BPH)ArmsAQUABEAM System, Transurethral Resection of the Prostate (TURP)
NCT03123250 nacompletednot on this map

Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue II

TypeinterventionalSponsorPROCEPT BioRoboticsRan2017 to 2022Enrolled101ConditionsBenign Prostatic Hyperplasia (BPH)ArmsAquablation
NCT04658056 unknown statusnot on this mapstarted 2021, after this paper: background citation

The UK POST WATERStudy: UK Post-market Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue

TypeobservationalSponsorPROCEPT BioRoboticsRan2021 to 2022Enrolled46ConditionsBenign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bilal ChughtaiWeill Cornell Medical College, New York, NY, USA. bic9008@med.cornell.edu.
Dominique ThomasWeill Cornell Medical College, New York, NY, USA.
Cornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo present short-term safety and efficacy data of men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) treated with Aquablation.

methodsMen with LUTs secondary to BPH (60-150 cc) underwent Aquablation treatment from February 2016 to December 2017 across 17 investigational sites in the USA from two contemporary investigational device exemption (IDE) studies called WATER (NCT02505919) and WATER II (NCT03123250).

resultsOne hundred seven males with mean age of 67.3 ± 6.5 years were treated with Aquablation; mean prostate volume was 99.4 ± 24.1 cc. The pooled results show that large prostates have an average procedure time of less than 36 min and discharge on average 1.6 ± 1 days. The IPSS decreased by 16.7 ± 8.1 points at 3 months and Q

conclusionMen with LUTS secondary to BPH (60-150 cc) in a pooled analysis were treated safely and effectively with Aquablation up to 3 months postoperatively.

trial registrationClinicalTrials.gov identifiers, NCT02505919 and NCT03123250.

fundingPROCEPT BioRobotics.

Indexed as

Ablation TechniquesAgedHumansLower Urinary Tract SymptomsMaleMiddle AgedProspective StudiesProstatic HyperplasiaTreatment OutcomeUnited StatesAquablationBPHLUTSProstate surgeryRoboticsUrology

Identifiers

PMID29873008
OpenAlexW2806313076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.