Evidence map›Paper›PMID 29872928›Full record

ArticleEuropean child & adolescent psychiatry2019

Increased risk of developing psychiatric disorders in children with attention deficit and hyperactivity disorder (ADHD) receiving sensory integration therapy: a population-based cohort study.

Ruu-Fen Tzang, Yue-Cune Chang, Kai-Liang Kao, Yu-Hsin Huang, Hui-Chun Huang, Yu-Chiao Wang, Chih-Hsin Muo, Shu-I Wu, Fung-Chang Sung, Robert Stewart

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Article in European child & adolescent psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Ruu-Fen TzangDepartment of Medicine, Mackay Medical College, Taipei, Taiwan.
Yue-Cune ChangDepartment of Mathematics, Tamkang University, Taipei, Taiwan.
Kai-Liang KaoDepartment of Pediatrics, Far Eastern Memorial Hospital, Taipei, Taiwan.
Yu-Hsin HuangDepartment of Medicine, Mackay Medical College, Taipei, Taiwan.
Hui-Chun HuangMackay Junior College of Medicine, Nursing and Management, Taipei, Taiwan.
Yu-Chiao WangManagement Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
Chih-Hsin MuoManagement Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
Shu-I Wu *Department of Medicine, Mackay Medical College, Taipei, Taiwan. shuiwu@g.ntu.edu.tw.ORCID http://orcid.org/0000-0002-8461-5613
Fung-Chang Sung *Department of Public Health, China Medical University, Taichung, Taiwan. fcsung1008@yahoo.com.
Robert StewartDepartment of Psychological Medicine, King's College London (Institute of Psychiatry, Psychology and Neuroscience), London, UK.
China Medical University · TWMackay Memorial Hospital · TWFar Eastern Memorial Hospital · TWKing's College London · GBTamkang University · TW

Funding

Medical Research Council MC_PC_17214
6 · The paper itself

Abstract

Parents of children with attention deficit hyperactivity disorder (ADHD) have been found to prefer sensory integration (SI) training rather than guideline-recommended ADHD treatment. This study investigated whether SI intervention for children with ADHD was associated with a reduced risk of subsequent mental disorders. From children < 8-years-old newly diagnosed with ADHD in a nationwide population-based dataset, we established a SI cohort and a non-SI cohort (N =  1945) matched by propensity score. Incidence and hazard ratios of subsequent psychiatric disorders were compared after a maximum follow-up of 9 years. The incidence of psychiatric disorders was 1.4-fold greater in the SI cohort, with an adjusted hazard ratio of 1.41 (95% confidence interval 1.20-1.67), comparing to the non-SI cohort. Risks were elevated for emotional disturbances, conduct disorders, and adjustment disorders independent of age, gender, or comorbidity. Among children with only psychosocial intervention, the incidence of psychiatric disorders was 3.5-fold greater in the SI cohort than in the non-SI cohort. To our knowledge, this is the first study to report an increased risk of developing psychiatric disorders for children with ADHD who received SI compared to those who did not. Potential adverse effects of SI for ADHD children should be carefully examined and discussed before practice.

Indexed as

Behavior TherapyAdolescentAttention Deficit Disorder with HyperactivityChildCohort StudiesComorbidityConduct DisorderFemaleHumansIncidenceMaleMental DisordersMood DisordersParentsProportional Hazards ModelsRisk FactorsAffective disorderAttention deficit and hyperactivity disorderConduct disorderNon-western countryPsychiatric disordersSensory integration

Identifiers

PMID29872928
OpenAlexW2805835890

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.