ArticleFrontiers in bioengineering and biotechnology2018
Development and Clinical Application of a Novel Autonomic Transient Response-Based Screening System for Major Depressive Disorder Using a Fingertip Photoplethysmographic Sensor.
Article in Frontiers in bioengineering and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- The tolerance-related psychology and dynamic activity in the peripheral nervous system of Internet gaming disorder during playing online games.Biomedical engineering online · 2025Article
- Remote photoplethysmography for health assessment: a review informed by IntelliProve technology.Frontiers in digital health · 2025Review
- The 2023 wearable photoplethysmography roadmap.Physiological measurement · 2023Review
- The Use of Photoplethysmography in the Assessment of Mental Health: Scoping Review.JMIR mental health · 2023Article
- Screening for Major Depressive Disorder Using a Wearable Ultra-Short-Term HRV Monitor and Signal Quality Indices.Sensors (Basel, Switzerland) · 2023Article
- The development and clinical application of a novel schizophrenia screening system using yoga-induced autonomic nervous system responses.Frontiers in physiology · 2022Article
- Extended classifier system with continuous real-coded variables for feature extraction of instantaneous pulse-rate variability and respiration of individuals with gaming disorder.Biomedical engineering online · 2021Article
- Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects.Sensors (Basel, Switzerland) · 2021Article
- Wearable, Environmental, and Smartphone-Based Passive Sensing for Mental Health Monitoring.Frontiers in digital health · 2021Review
- Development of a Novel Web Camera-Based Contact-Free Major Depressive Disorder Screening System Using Autonomic Nervous Responses Induced by a Mental Task and Its Clinical Application.Frontiers in physiology · 2021Article
- Sex-Specific Differences in Severity of Depressive Symptoms, Heart Rate Variability, and Neurocognitive Profiles of Depressed Young Adults: Exploring Characteristics for Mild Depression.Frontiers in psychiatry · 2020Article
- Development and Clinical Application of a Novel Non-contact Early Airflow Limitation Screening System Using an Infrared Time-of-Flight Depth Image Sensor.Frontiers in physiology · 2020Article
- Heart Rate Variability (HRV) and Pulse Rate Variability (PRV) for the Assessment of Autonomic Responses.Frontiers in physiology · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over 350 million people across the world suffer from major depressive disorder (MDD). More than 10% of MDD patients have suicide intent, while it has been reported that more than 40% patients did not consult their doctors for MDD. In order to increase consultation rate of potential MDD patients, we developed a novel MDD screening system which can be used at home without help of health-care professionals. Using a fingertip photoplethysmograph (PPG) sensor as a substitute of electrocardiograph (ECG), the system discriminates MDD patients from healthy subjects using autonomic nerve transient responses induced by a mental task (random number generation) via logistic regression analysis. The nine logistic regression variables are averages of heart rate (HR), high frequency (HF) component of heart rate variability (HRV), and the low frequency (LF)/HF ratio of HRV before, during, and after the mental task. We conducted a clinical test of the proposed system. Participants were 6 MDD patients (4 females and 2 males, aged 23-60 years) from Shizuoka Saiseikai General Hospital psychiatry outpatient unit and 14 healthy volunteers from University of Electro-Communications (6 females and 8 males, aged 21-63 years). The average PPG- and ECG (as a reference)-derived HR, HF and LF/HF were significantly correlated with each other (HR;
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