Evidence map›Paper›PMID 29872655›Full record

ArticleFrontiers in bioengineering and biotechnology2018

Glucose-Dependent Promoters for Dynamic Regulation of Metabolic Pathways.

Jérôme Maury, Soumya Kannan, Niels B Jensen, Fredrik K Öberg, Kanchana R Kildegaard, Jochen Forster, Jens Nielsen, Christopher T Workman, Irina Borodina

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Balancing Cell Growth and Product Synthesis for Efficient Microbial Cell Factories.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Minimizing acetate formation from overflow metabolism inFrontiers in bioengineering and biotechnology · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Genome Assembly and Genetic Traits of the Pleuromutilin-ProducerJournal of fungi (Basel, Switzerland) · 2022
    Article
  11. Saccharomyces cerevisiae as a Heterologous Host for Natural Products.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  12. Article
  13. Review
  14. Effect of Isomixing on Grape Must Fermentations ofFoods (Basel, Switzerland) · 2020
    Article
  15. Engineering Expression Cassette ofFrontiers in bioengineering and biotechnology · 2020
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jérôme MauryNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Soumya KannanDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Niels B JensenNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Fredrik K ÖbergNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Kanchana R KildegaardNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Jochen ForsterNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Jens NielsenNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Christopher T WorkmanDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Irina BorodinaNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Novo Nordisk Foundation · DKTechnical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For an industrial fermentation process, it can be advantageous to decouple cell growth from product formation. This decoupling would allow for the rapid accumulation of biomass without inhibition from product formation, after which the fermentation can be switched to a mode where cells would grow minimally and primarily act as catalysts to convert substrate into desired product. The switch in fermentation mode should preferably be accomplished without the addition of expensive inducers. A common cell factory

Indexed as

3-hydroxypropionic aciddynamic regulationinducible promotersstrain engineeringyeast Saccharomyces cerevisiae

Identifiers

PMID29872655
PMCPMC5972318
OpenAlexW2802849228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.