Evidence map›Paper›PMID 29872531›Full record

ArticleNew microbes and new infections2018

Rapid detection and monitoring of human coronavirus infections.

A H L Bruning, H Aatola, H Toivola, N Ikonen, C Savolainen-Kopra, S Blomqvist, D Pajkrt, K C Wolthers, J O Koskinen

Open access · goldAbstract read
In one paragraph

Article in New microbes and new infections, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Nanomaterials-based sensors for the detection of COVID-19: A review.Bioengineering & translational medicine · 2022
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Modern Tools for Rapid Diagnostics of Antimicrobial Resistance.Frontiers in cellular and infection microbiology · 2020
    Review
  17. Review
  18. COVID-19 in Children: An Ample Review.Risk management and healthcare policy · 2020
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

A H L BruningDepartment of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands.
H AatolaArcDia International Oy Ltd, Turku, Finland.
H ToivolaArcDia International Oy Ltd, Turku, Finland.
N IkonenNational Institute for Health and Welfare (THL), Helsinki, Finland.
C Savolainen-KopraNational Institute for Health and Welfare (THL), Helsinki, Finland.
S BlomqvistNational Institute for Health and Welfare (THL), Helsinki, Finland.
D PajkrtDepartment of Pediatric Infectious Diseases, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
K C WolthersDepartment of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands.
J O KoskinenArcDia International Oy Ltd, Turku, Finland.
Finnish Institute for Health and Welfare · FIAcademic Medical Center · NLEmma Kinderziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human coronaviruses (CoVs) are increasingly recognized as important respiratory pathogens associated with a broad range of clinical diseases. We sought to increase the insight into clinically relevant CoV infections by monitoring antigen concentrations in six confirmed CoV-positive patients using a newly developed assay for rapid detection of CoV OC43 infections. Antigen positivity lasted 3 to 6 days in secondary infections and 13 days in primary infection. CoV infections are clinically diverse, are common, and cannot be diagnosed from clinical symptoms alone.

Indexed as

Human coronaviruspoint-of-care testrapid antigen testrapid detectionrespiratory tract infection

Identifiers

PMID29872531
PMCPMC5986163
OpenAlexW2800774218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.