Evidence map›Paper›PMID 29872469›Full record

ReviewEuropean endocrinology2014

Osteoporosis in Human Immunodeficiency Virus Patients - An Emerging Clinical Concern.

Filippo Maffezzoni, Teresa Porcelli, Ioannis Karamouzis, Eugenia Quiros-Roldan, Francesco Castelli, Gherardo Mazziotti, Andrea Giustina

Open access · bronzeAbstract readReview
In one paragraph

Review in European endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Role of bone mineral density in predicting morphometric vertebral fractures in patients with HIV infection.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Filippo MaffezzoniClinical Fellow, Division of Endocrinology.
Teresa PorcelliEndocrinologist, Division of Endocrinology.
Ioannis KaramouzisEndocrinologist, Division of Endocrinology.
Eugenia Quiros-RoldanClinical Researcher, Division of Infectious Diseases.
Francesco CastelliFull Professor, Division of Infectious Diseases.
Gherardo MazziottiAssistant Professor, Division of Endocrinology.
Andrea GiustinaFull Professor, Division of Endocrinology, Department of Clinical and Experimental Sciences, University of Brescia, Italy.
Endocrine Society · USCenter for Clinical Research (United States) · USH.B. Fuller (United States) · USInfectious Clinical Hospital No. 1 · RUOrthopedic Center · USUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advent of highly active anti-retroviral therapy (HAART) has significantly improved the survival of human immunodeficiency virus (HIV)-infected patients transforming the HIV infection from a fatal illness into a manageable chronic disease. As the number of older HIV-infected individuals increases, several ageing-related co-morbidities including osteopenia/osteoporosis and fractures have emerged. Patients exposed to HIV infection and its treatment may develop fragility fractures with potential significant impact on quality of life and survival. However, the awareness of HIV-related skeletal fragility is still relatively low and most HIV-infected patients are not investigated for osteoporosis and treated with anti-osteoporotic drugs in daily clinical practice. This article reviews the literature data on osteoporosis and osteopenia in HIV infection, focusing on the pathophysiological, clinical and therapeutic aspects of fragility fractures.

Indexed as

fracturesHAARTHIVosteoporosisretroviral drugs

Identifiers

PMID29872469
PMCPMC5983102
OpenAlexW2491067961

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.