Evidence map›Paper›PMID 29872436›Full record

ArticleFrontiers in immunology2018

T Cell Receptor Alpha Chain Genes in the Teleost Ballan Wrasse

Sumaira Bilal, Kai Kristoffer Lie, Øystein Sæle, Ivar Hordvik

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sumaira BilalDepartment of Biological Sciences, University of Bergen, Bergen, Norway.
Kai Kristoffer LieInstitute of Marine Research (IMR), Bergen, Norway.
Øystein SæleInstitute of Marine Research (IMR), Bergen, Norway.
Ivar HordvikDepartment of Biological Sciences, University of Bergen, Bergen, Norway.
Norwegian Institute of Marine Research · NOUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously, somatic hypermutation (SHM) was considered to be exclusively associated with affinity maturation of antibodies, although it also occurred in T cells under certain conditions. More recently, it has been shown that SHM generates diversity in the variable domain of T cell receptor (TCR) in camel and shark. Here, we report somatic mutations in TCR alpha chain genes of the teleost fish, Ballan wrasse (

Indexed as

Genes, T-Cell Receptor alphaSomatic Hypermutation, ImmunoglobulinAmino Acid SequenceAnimalsChromosome MappingComputational BiologyDNA, ComplementaryFishesGenomeGenomicsHigh-Throughput Nucleotide SequencingMutationPolymorphism, Single NucleotideDNA, Complementaryactivation-induced cytidine deaminase motifballan wrassepolymorphismsomatic hypermutationT cell receptorTCRαteleost

Identifiers

PMID29872436
PMCPMC5972329
OpenAlexW2803839777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.