ReviewFrontiers in neurology2018
Shining a Light on Awareness: A Review of Functional Near-Infrared Spectroscopy for Prolonged Disorders of Consciousness.
Review in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 60 citations in OpenAlex.
- Binary Classification of Consciousness Using Cerebral Blood Flow and EEG Features.Neurocritical care · 2026Article
- NIRSLINK: A Modular Cascaded Wearable Near-Infrared Spectroscopy System for High-Speed Multi-Site Hemodynamic Monitoring.Biosensors · 2026Article
- Regional tissue perfusion index (RTPI): a new optical-based metric for quantifying regional tissue perfusion.Journal of clinical monitoring and computing · 2026Article
- Cortical processing modulation in DOC by preferred music-coupled 40 Hz binaural stimulation: an exploratory EEG-fNIRS study.Frontiers in psychology · 2026Article
- Multimodal biomarkers of response to transcutaneous auricular vagus nerve stimulation in disorders of consciousness: a study protocol.Frontiers in human neuroscience · 2026Article
- Functional near-infrared spectroscopy for the assessment and treatment of patients with disorders of consciousness.Frontiers in neurology · 2025Review
- ninjaNIRS: an open hardware solution for wearable whole-head high-density functional near-infrared spectroscopy.Biomedical optics express · 2024Article
- Unlocking the neural mechanisms of consumer loan evaluations: an fNIRS and ML-based consumer neuroscience study.Frontiers in human neuroscience · 2024Article
- Assessing the consistency and sensitivity of the neural correlates of narrative stimuli using functional near-infrared spectroscopy.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Differences in the effect of repetitive transcranial magnetic stimulation and median nerve electrical stimulation in patients with prolonged disorders of consciousness after intracerebral hemorrhage: a randomized controlled trial protocol.Frontiers in neurology · 2024Article
- Variability of large timescale functional networks in patients with disorders of consciousness.Frontiers in neurology · 2024Article
- Recovering fetal signals transabdominally through interferometric near-infrared spectroscopy (iNIRS).Biomedical optics express · 2023Article
- A functional near-infrared spectroscopy study on hemodynamic changes of patients with prolonged disorders of consciousness responding to different auditory stimuli.BMC neurology · 2023Article
- Evaluation of residual cognition in patients with disorders of consciousness based on functional near-infrared spectroscopy.Neurophotonics · 2023Article
- Assessment and management of pain/nociception in patients with disorders of consciousness or locked-in syndrome: A narrative review.Frontiers in systems neuroscience · 2023Review
- Disturbed functional connectivity and topological properties of the frontal lobe in minimally conscious state based on resting-state fNIRS.Frontiers in neuroscience · 2023Article
- Brain bases of English morphological processing: A comparison between Chinese-English, Spanish-English bilingual, and English monolingual children.Developmental science · 2023Article
- Applications of functional near-infrared spectroscopy in non-drug therapy of traditional Chinese medicine: a review.Frontiers in neuroscience · 2023Review
- Evaluation of consciousness rehabilitation via neuroimaging methods.Frontiers in human neuroscience · 2023Review
- Optical imaging and spectroscopy for the study of the human brain: status report.Neurophotonics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Qualitative clinical assessments of the recovery of awareness after severe brain injury require an assessor to differentiate purposeful behavior from spontaneous behavior. As many such behaviors are minimal and inconsistent, behavioral assessments are susceptible to diagnostic errors. Advanced neuroimaging tools can bypass behavioral responsiveness and reveal evidence of covert awareness and cognition within the brains of some patients, thus providing a means for more accurate diagnoses, more accurate prognoses, and, in some instances, facilitated communication. The majority of reports to date have employed the neuroimaging methods of functional magnetic resonance imaging, positron emission tomography, and electroencephalography (EEG). However, each neuroimaging method has its own advantages and disadvantages (e.g., signal resolution, accessibility, etc.). Here, we describe a burgeoning technique of non-invasive optical neuroimaging-functional near-infrared spectroscopy (fNIRS)-and review its potential to address the clinical challenges of prolonged disorders of consciousness. We also outline the potential for simultaneous EEG to complement the fNIRS signal and suggest the future directions of research that are required in order to realize its clinical potential.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.