ReviewFrontiers in pharmacology2018
Anticancer Activity and Mechanism of Xanthohumol: A Prenylated Flavonoid From Hops (
Review in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
119 citing papers in PubMed, 2 syntheses or guidelines pooled it, 261 citations in OpenAlex.
- Natural flavonoid isoorientin and its anticancer mechanisms: a systematic review.Naunyn-Schmiedeberg's archives of pharmacology · 2026Pooled it
- Citrus Flavonoids as Promising Phytochemicals Targeting Diabetes and Related Complications: A Systematic Review of In Vitro and In Vivo Studies.Nutrients · 2020Pooled it
- Inhibition effects and binding interactions of epigallocatechin and gallocatechin on tyrosinase and their anti-melanogenesis activity.Journal of enzyme inhibition and medicinal chemistry · 2026Article
- Palmitic acid in cancer research: mechanistic insights from in vitro and in vivo studies.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Selective Anticancer Effects of Portulaca grandiflora via Apoptosis and NF-κB Pathway Modulation in MDA-MB-231 Cells.Applied biochemistry and biotechnology · 2026Article
- Vitamin D₃ in cancer prevention and therapy: molecular mechanisms, clinical evidence, and future perspectives.Molecular biology reports · 2026Review
- Synthesis and biological evaluation of bisspirooxindole-hexahydroindolizines as potential anticancer agent.Molecular diversity · 2026Article
- Biopolymer Surface Modification as a Strategy for Conferring "Stealth-like" Characteristics of Xanthohumol-Loaded Liposomes.Polymers · 2026Article
- Natural Products Targeting Oxidative Stress-Inflammation Crosstalk in Endometriosis.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Review
- Knowledge and Perception of Cervical Cancer and Pap-Smear Screening Among Antenatal Women in Ogun State, Nigeria.Cancer medicine · 2026Article
- Exploring anticancer drug structures through vertex based resolving parameters.Scientific reports · 2026Article
- Agro-Industrial Plant Biomass as a Sustainable Source of Anticancer Polyphenols: Molecular Mechanisms and Future Perspectives.Current issues in molecular biology · 2026Review
- Biological Activity of Hops (Nutrients · 2026Review
- Eriodictyol in Cancer Therapy: Reviewing Mechanistic Insights and Translational Opportunities.International journal of molecular sciences · 2026Review
- Exploring the Potential of Hop (Plants (Basel, Switzerland) · 2026Article
- Exploring the Multifaceted Phytochemical Profile ofPharmaceuticals (Basel, Switzerland) · 2026Article
- Article
- Biosynthesis of silver nanoparticles via Melaleuca alternifolia leaf extract for antibacterial, antifungal, antioxidant and anticancer activity.Scientific reports · 2026Article
- Biological Effects of Calceolarioside A as a Natural Compound: Anti-Ovarian Cancer, Anti-Tyrosinase, and Anti-HMG-CoA Reductase Potentials with Molecular Docking and Dynamics Simulation Studies.Molecular biotechnology · 2026Article
- From bench to bedside: unlocking the anti-inflammatory, antioxidant, and anticancer promise of curcumin in gynecology.Frontiers in medicine · 2026Review
59 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been observed that many phytochemicals, frequently present in foods or beverages, show potent chemopreventive or therapeutic properties that selectively affect cancer cells. Numerous studies have demonstrated the anticancer activity of xanthohumol (Xn), a prenylated flavonoid isolated from hops (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.