Evidence map›Paper›PMID 29872379›Full record

ArticleFrontiers in neural circuits2018

HOPE: Hybrid-Drive Combining Optogenetics, Pharmacology and Electrophysiology.

Sebastien Delcasso, Sachira Denagamage, Zelie Britton, Ann M Graybiel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neural circuits, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Multimodal Layer-Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sebastien DelcassoDepartment of Brain and Cognitive Sciences, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, United States.
Sachira DenagamageDepartment of Brain and Cognitive Sciences, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, United States.
Zelie BrittonDepartment of Brain and Cognitive Sciences, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, United States.
Ann M GraybielDepartment of Brain and Cognitive Sciences, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, United States.
McGovern Institute for Brain Research · USMassachusetts Institute of Technology · US

Funding

Functional and anatomical characterization of the striosomal systemR01MH060379 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Ann M Graybiel · 2000 to 2026
$8.7M
NIMH NIH HHS R01 MH060379
6 · The paper itself

Abstract

Understanding the neural mechanisms underlying human cognition and determining the causal factors for the development of brain pathologies are among the greatest challenges for society. Electrophysiological recordings offer remarkable observations of brain activity as they provide highly precise representations of information coding in both temporal and spatial domains. With the development of genetic tools over the last decades, mice have been a key model organism in neuroscience. However, conducting chronic

Indexed as

Electrodes, ImplantedOptogeneticsAnimalsBehavior, AnimalBrainElectrophysiological PhenomenaElectrophysiologyMiceWakefulnessdrug deliveryelectrode arrayelectrophysiologymicrodrivemulti-siteoptogenetics

Identifiers

PMID29872379
PMCPMC5972628
OpenAlexW2803665283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.