ArticleInternational journal of nanomedicine2018
Bilirubin detoxification using different phytomaterials: characterization and in vitro studies.
Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- The use of minerals, plants and burnt materials in ancient medicine: Approaches to working recipes in John the Physician'sProceedings of the Geologists' Association. Geologists' Association · 2026Article
- Recent Advances in Mesoporous Silica Nanoparticles Delivering siRNA for Cancer Treatment.Pharmaceutics · 2023Review
- Characterization of graphene oxide-ziziphus seeds and its application as a hazardous dye removal adsorbent.Scientific reports · 2023Article
- Characterization of Date Seed Powder Derived Porous Graphene Oxide and Its Application as an Environmental Functional Material to Remove Dye from Aqueous Solutions.Materials (Basel, Switzerland) · 2022Article
- Evaluation of cytotoxicity, oxidative stress and organ-specific effects of activated carbon from Al-Baha date palm kernels.Saudi journal of biological sciences · 2022Article
- Safety evaluation and ibuprofen removal via an Alternanthera philoxeroides-based biochar.Environmental science and pollution research international · 2021Article
- Halotolerant Marine Rhizosphere-Competent Actinobacteria PromoteFrontiers in microbiology · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundActivated carbon (AC) is a common adsorbent that is used in both artificial and bioartificial liver devices.
methodsThree natural materials - date pits of
resultsCompared with the other raw materials examined, date-pit AC was highly selective and showed the most effective capacity of bilirubin adsorption, as judged by isotherm-modeling analysis. MTT in vitro analysis indicated that date-pit AC had the least effect on the viability of both THLE2 and HepG2 cells compared to jojoba seeds and microalgae. All three biomaterials under investigation were used, along with collagen and Matrigel, to grow cells in 3D culture. Fluorescent microscopy confirmed date-pit AC as the best to preserve liver cell integrity.
conclusionThe findings of this study introduce date-pit-based AC as a novel alternative biomaterial for the removal of protein-bound toxins in bioartificial liver devices.
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