Evidence map›Paper›PMID 29872291›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2018

Genetic variants in FAM13A and IREB2 are associated with the susceptibility to COPD in a Chinese rural population: a case-control study.

Yanan Zhang, Jie Qiu, Peng Zhang, Jin Zhang, Min Jiang, Zhanbing Ma

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Single Nucleotide Polymorphisms ofAdvances in respiratory medicine · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Differential Genomic Profile inFrontiers in medicine · 2021
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yanan ZhangDepartment of Respiratory and Critical Care Medicine, General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan, People's Republic of China.
Jie QiuDepartment of Respiratory and Critical Care Medicine, General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan, People's Republic of China.
Peng ZhangDepartment of Respiratory and Critical Care Medicine, General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan, People's Republic of China.
Jin ZhangDepartment of Respiratory and Critical Care Medicine, General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan, People's Republic of China.
Min JiangNational Engineering Research Center for Beijing Biochip Technology, Sub-center in Ningxia, General Hospital of Ningxia Medical University, Yinchuan, People's Republic of China.
Zhanbing MaDepartment of Medical Genetic and Cell Biology, Ningxia Medical University, Yinchuan, People's Republic of China.
General Department of Preventive Medicine · VNNingxia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Genome-wide association studies identified several genomic regions associated with the risk of chronic obstructive pulmonary disease (COPD), including the 4q22 and 15q25 regions. These regions contain the Methods: This was a case-control study performed in the Ningxia Hui Autonomous Region between January 2014 and December 2016. Patients were grouped as COPD and controls based on FEV Results: rs17014601 in FAM13A was significantly associated with COPD in the additive (odds ratio [OR]=1.36, 95% confidence interval [CI]: 1.11-1.67, Conclusion: The results suggest that the new variant rs17014601 in the

Indexed as

Polymorphism, Single NucleotideAdultCase-Control StudiesChinaFemaleGenetic Predisposition to DiseaseGenetic VariationGenome-Wide Association StudyGTPase-Activating ProteinsHumansIron Regulatory Protein 2MaleMiddle AgedNon-SmokersProspective StudiesPulmonary Disease, Chronic ObstructiveFAM13A protein, humanGTPase-Activating ProteinsIron Regulatory Protein 2chronic obstructive pulmonary diseaseFAM13AIREB2single-nucleotide polymorphism

Identifiers

PMID29872291
PMCPMC5973397
OpenAlexW2804452479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.