ArticleScientific reports2018
Lateral intraparietal area (LIP) is largely effector-specific in free-choice decisions.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Dorsal pulvinar inactivation leads to spatial selection bias without perceptual deficit.Scientific reports · 2024Article
- Decision-making processes in perceptual learning depend on effectors.Scientific reports · 2024Article
- Decoding motor plans using a closed-loop ultrasonic brain-machine interface.Nature neuroscience · 2024Article
- Neuronal Response to Reward and Luminance in Macaque LIP During Saccadic Choice.Neuroscience bulletin · 2023Article
- Deficits in decision-making induced by parietal cortex inactivation are compensated at two timescales.Neuron · 2022Article
- Hand choice is unaffected by high frequency continuous theta burst transcranial magnetic stimulation to the posterior parietal cortex.PloS one · 2022Article
- Action planning and control under uncertainty emerge through a desirability-driven competition between parallel encoding motor plans.PLoS computational biology · 2021Article
- Distinct saccade planning and endogenous visuospatial attention maps in parietal cortex: A basis for functional differences in sensory and motor attention.Cortex; a journal devoted to the study of the nervous system and behavior · 2021Article
- Decoding the neural dynamics of free choice in humans.PLoS biology · 2020Article
- The functional roles of neural remapping in cortex.Journal of vision · 2020Article
- Reaching decisions during ongoing movements.Journal of neurophysiology · 2020Article
- Effects of the Openness to Experience Polygenic Score on Cortical Thickness and Functional Connectivity.Frontiers in neuroscience · 2020Article
- No one knows what attention is.Attention, perception & psychophysics · 2019Review
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3 authors.
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Abstract
Despite many years of intense research, there is no strong consensus about the role of the lateral intraparietal area (LIP) in decision making. One view of LIP function is that it guides spatial attention, providing a "saliency map" of the external world. If this were the case, it would contribute to target selection regardless of which action would be performed to implement the choice. On the other hand, LIP inactivation has been shown to influence spatial selection and oculomotor metrics in free-choice decisions, which are made using eye movements, arguing that it contributes to saccade decisions. To dissociate between a more general attention role and a more effector specific saccade role, we reversibly inactivated LIP while non-human primates freely selected between two targets, presented in the two hemifields, with either saccades or reaches. Unilateral LIP inactivation induced a strong choice bias to ipsilesional targets when decisions were made with saccades. Interestingly, the inactivation also caused a reduction of contralesional choices when decisions were made with reaches, albeit the effect was less pronounced. These findings suggest that LIP is part of a network for making oculomotor decisions and is largely effector-specific in free-choice decisions.
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