Evidence map›Paper›PMID 29871931›Full record

ArticleThe Journal of biological chemistry2018

Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1).

Ken Noguchi, Toros A Dincman, Annamarie C Dalton, Breege V Howley, Buckley J McCall, Bidyut K Mohanty, Philip H Howe

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Neutrophils promote tumor invasionInternational journal of biological sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ken NoguchiDepartment of Biochemistry and Molecular Biology, College of Medicine, Charleston, South Carolina 29425.
Toros A DincmanDepartment of Biochemistry and Molecular Biology, College of Medicine, Charleston, South Carolina 29425; Division of Hematology and Oncology, Medical University of South Carolina, Charleston, South Carolina 29425.
Annamarie C DaltonDepartment of Biochemistry and Molecular Biology, College of Medicine, Charleston, South Carolina 29425.
Breege V HowleyDepartment of Biochemistry and Molecular Biology, College of Medicine, Charleston, South Carolina 29425.
Buckley J McCallDepartment of Biochemistry and Molecular Biology, College of Medicine, Charleston, South Carolina 29425.
Bidyut K MohantyDepartment of Biochemistry and Molecular Biology, College of Medicine, Charleston, South Carolina 29425.
Philip H HoweDepartment of Biochemistry and Molecular Biology, College of Medicine, Charleston, South Carolina 29425; Hollings Cancer Center, Charleston, South Carolina 29425. Electronic address: howep@musc.edu.
College of Charleston · USMedical University of South Carolina · US

Funding

TGF-regulated EMTR01CA154663 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Philip H Howe · 2011 to 2026
$5.1M
Integrative Training in Oncogenic SignalingT32CA193201 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HOWE, PHILIP H, LONG, DAVID THOMAS · 2016 to 2025
$3.7M
The Role of JAK2 in ILEI-Induced Cancer Stem Cell FormationF30CA203269 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI NOGUCHI, KEN · 2016 to 2019
$161k
NCI NIH HHS F30 CA203269NCI NIH HHS R01 CA154663NCI NIH HHS T32 CA193201
6 · The paper itself

Abstract

Interleukin-like EMT inducer (ILEI,

Indexed as

Transcriptional ActivationAnimalsCell LineCell Line, TumorCells, CulturedCytokinesEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansMelanomaMiceNeoplasm InvasivenessNeoplasm ProteinsUp-RegulationUpstream Stimulatory FactorsCytokinesFAM3C protein, humanFam3c protein, mouseNeoplasm ProteinsUpstream Stimulatory FactorsUSF1 protein, humanUsf1 protein, mousecytokineepithelial-mesenchymal transition (EMT)FAM3CILEIinterleukin-like EMT inducermelanomamRNAphenotype switchingtranscription factorUSF-1

Identifiers

PMID29871931
PMCPMC6065179
OpenAlexW2805085456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.