Evidence map›Paper›PMID 29871925›Full record

ArticleThe Journal of biological chemistry2018

The CCCH-type zinc finger transcription factor Zc3h8 represses NF-κB-mediated inflammation in digestive organs in zebrafish.

Qingliang Zou, Kai Gang, Qifen Yang, Xiaolin Liu, Xuemei Tang, Huiqiang Lu, Jianbo He, Lingfei Luo

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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  8. Knockout fth1b affects early mineralization of zebrafish pharyngeal teeth.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qingliang ZouKey Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Kai GangKey Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Qifen YangKey Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Xiaolin LiuKey Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Xuemei TangKey Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Huiqiang LuKey Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Jianbo HeKey Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Lingfei LuoKey Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China. Electronic address: lluo@swu.edu.cn.
Southwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degenerative diseases of organs lead to their impaired function. The cellular and molecular mechanisms underlying organ degeneration are therefore of great research and clinical interest but are currently incompletely characterized. Here, using a forward-genetic screen for genes regulating liver development and function in zebrafish, we identified a

Indexed as

Amino Acid SequenceAnimalsApoptosisCell ProliferationCytokinesEmbryo, NonmammalianGene Expression Regulation, DevelopmentalGlutamineHepatocytesHistidineInflammationIntestinesLiverMacrophagesMutationNF-kappa BCytokinesGlutamineHistidineNF-kappa BTranscription FactorsZebrafish Proteinscell signalingdegenerationdigestive organinflammationNF-κ B (NF-κB)zebrafishzinc finger

Identifiers

PMID29871925
PMCPMC6078438
OpenAlexW2806587776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.