Evidence map›Paper›PMID 29871918›Full record

ArticlemBio2018

Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers.

Stefanie Allert, Toni M Förster, Carl-Magnus Svensson, Jonathan P Richardson, Tony Pawlik, Betty Hebecker, Sven Rudolphi, Marc Juraschitz, Martin Schaller, Mariana Blagojevic and 7 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 190 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Detection of Fungal Translocation in Patients With Alcohol Use Disorder Using a Real-Time PCR Assay.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Article
  10. Article
  11. Review
  12. Yeasts in the gastrointestinal tract.FEMS yeast research · 2026
    Review
  13. Fungal Reactive Oxygen Species Secreted byJournal of fungi (Basel, Switzerland) · 2026
    Article
  14. Review
  15. Review
  16. Review
  17. microLife · 2026
    Article
  18. Article
  19. Gut microbes · 2025
    Article
  20. mBio · 2025
    Article

79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Stefanie Allert *Department of Microbial Pathogenicity Mechanisms, Hans-Knöll-Institute, Jena, Germany.ORCID 0000-0003-0823-4824
Toni M Förster *Department of Microbial Pathogenicity Mechanisms, Hans-Knöll-Institute, Jena, Germany.
Carl-Magnus SvenssonResearch Group Applied Systems Biology, Hans-Knöll-Institute, Jena, Germany.
Jonathan P RichardsonMucosal & Salivary Biology Division, Dental Institute, King's College London, London, United Kingdom.
Tony PawlikResearch Group Microbial Immunology, Hans-Knöll-Institute, Jena, Germany.
Betty HebeckerDepartment of Microbial Pathogenicity Mechanisms, Hans-Knöll-Institute, Jena, Germany.
Sven RudolphiResearch Group Microbial Immunology, Hans-Knöll-Institute, Jena, Germany.
Marc JuraschitzDepartment of Microbial Pathogenicity Mechanisms, Hans-Knöll-Institute, Jena, Germany.
Martin SchallerDepartment of Dermatology, University Hospital Tübingen, Tübingen, Germany.
Mariana BlagojevicMucosal & Salivary Biology Division, Dental Institute, King's College London, London, United Kingdom.
Joachim MorschhäuserInstitute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Marc Thilo FiggeResearch Group Applied Systems Biology, Hans-Knöll-Institute, Jena, Germany.ORCID 0000-0002-4044-9166
Ilse D JacobsenResearch Group Microbial Immunology, Hans-Knöll-Institute, Jena, Germany.
Julian R NaglikMucosal & Salivary Biology Division, Dental Institute, King's College London, London, United Kingdom.
Lydia KasperDepartment of Microbial Pathogenicity Mechanisms, Hans-Knöll-Institute, Jena, Germany.
Selene MogaveroDepartment of Microbial Pathogenicity Mechanisms, Hans-Knöll-Institute, Jena, Germany.ORCID 0000-0003-0642-0068
Bernhard HubeDepartment of Microbial Pathogenicity Mechanisms, Hans-Knöll-Institute, Jena, Germany bernhard.hube@leibniz-hki.de.ORCID 0000-0002-6028-0425
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEKing's College London · GBUniversity Children's Hospital Tübingen · DEUniversity of Aberdeen · GBUniversity of Würzburg · DE

Funding

Host and Fungal Regulation of Type 17 Immunity to Oral CandidiasisR37DE022550 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Sarah L Gaffen · 2017 to 2026
$5.6M
Biotechnology and Biological Sciences Research Council BB/N014677/1Medical Research Council MC_PC_16048Medical Research Council MR/J008303/1Medical Research Council MR/M011372/1NIDCR NIH HHS R37 DE022550
6 · The paper itself

Abstract

Life-threatening systemic infections often occur due to the translocation of pathogens across the gut barrier and into the bloodstream. While the microbial and host mechanisms permitting bacterial gut translocation are well characterized, these mechanisms are still unclear for fungal pathogens such as

Indexed as

ApoptosisCandida albicansCandidiasisEnterocytesEpithelial CellsHost-Pathogen InteractionsHumansIntestinal MucosaIntestinesCandida albicanscandidalysinhost cell damagehost cell invasionintestinal barriernecrosistranslocation

Identifiers

PMID29871918
PMCPMC5989070
OpenAlexW2806470471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.