Evidence map›Paper›PMID 29871822›Full record

ReviewTrends in cell biology2018

The Lung and Esophagus: Developmental and Regenerative Overlap.

Edward E Morrisey, Anil K Rustgi

Abstract readReview
In one paragraph

Review in Trends in cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. SOX2 and SOX21 in Lung Epithelial Differentiation and Repair.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Article
  9. Minimum Esophageal Resection Length to Ensure Negative Proximal Margin in Total Gastrectomy for Gastric Cancer: A Retrospective Study.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022
    Article
  10. Lung epithelium development and airway regeneration.Frontiers in cell and developmental biology · 2022
    Review
  11. Article
  12. A 'tad' of hope in the fight against airway disease.Biochemical Society transactions · 2020
    Review
  13. Article
  14. mFrontiers in oncology · 2020
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Edward E MorriseyDivision of Cardiovascular Medicine, Center for Pulmonary Biology, Cardiovascular Institute, Institute for Regenerative Medicine, Abramson Cancer Center, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address: emorrise@pennmedicine.upenn.edu.
Anil K RustgiDivision of Gastroenterology, Departments of Medicine and Genetics, Institute for Regenerative Medicine, Abramson Cancer Center, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address: anil2@pennmedicine.upenn.edu.

Funding

Editing Alveolar Progenitor Cells for Correction of Monogenic DiseaseU01HL134745 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI KOTTON, DARRELL N., MORRISEY, EDWARD E · 2016 to 2022
$8.3M
Wnt signaling in the alveolar nicheR01HL087825 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MORRISEY, EDWARD E · 2008 to 2021
$6.4M
Molecular pathways controlling alveolar epithelial remodeling in development and regenerationR01HL132999 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MORRISEY, EDWARD E · 2016 to 2023
$4.6M
Epigenic Regulation of Lung Progenitor Repair and RegenerationU01HL110942 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MORRISEY, EDWARD E · 2012 to 2016
$3.4M
Developmental pathways regulating adult lung quiescenceR01HL132349 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MORRISEY, EDWARD E · 2016 to 2019
$2.3M
NHLBI NIH HHS R01 HL087825NHLBI NIH HHS R01 HL132349NHLBI NIH HHS R01 HL132999NHLBI NIH HHS U01 HL110942NHLBI NIH HHS U01 HL134745
6 · The paper itself

Abstract

Lung and esophageal development and organogenesis involve a complex interplay of signaling pathways and transcriptional factors. Once the lung and esophagus do separate, their epithelial proliferation and differentiation programs share certain common properties that may fuel adaptive responses to injury and subsequent regeneration. Lung and esophageal tissue organogenesis and regeneration provide perspectives on squamous cell cancers and adenocarcinomas in each tissue.

Indexed as

CarcinogenesisCell DifferentiationEsophagusGene Regulatory NetworksHumansLungRegenerationdevelopmentesophaguslungregenerationSox2Trp63

Identifiers

PMID29871822
PMCPMC6102049

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.