ArticleKidney & blood pressure research2018
Association of Intradialytic Hypertension with Left Ventricular Mass in Hypertensive Hemodialysis Patients Enrolled in the Blood Pressure in Dialysis (BID) Study.
Article in Kidney & blood pressure research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Pooled it
- Accurate prediction of intradialytic hypo- and hypertension in haemodialysis patients: the dual-attention Transformer model.Clinical kidney journal · 2026Article
- Article
- Parameters of Systolic and Diastolic Dysfunction in Patients with Intradialytic Hypertension.American journal of nephrology · 2025Article
- Prediction Model of Intradialytic Hypertension in Hemodialysis Patients Based on Machine Learning.Journal of medical systems · 2025Article
- Intradialytic hypertension: epidemiology and pathophysiology of a silent killer.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Review
- Assessing accuracy of estimated dry weight in dialysis patients post transplantation: the kidney knows best.Journal of nephrology · 2021Observational
- Dataset supporting blood pressure prediction for the management of chronic hemodialysis.Scientific data · 2019Article
- Cardiac Imaging in Dialysis Patients.Kidney medicineReview
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 1 country.
Funding
Abstract
BACKGROUND/
aimsIntradialytic hypertension (IDH), or paradoxical rise in blood pressure (BP) during hemodialysis (HD) is associated with increased morbidity and mortality. The association between IDH and increased left ventricular mass (LVM), a well-known risk factor for adverse cardiovascular outcomes in HD patients, has not been studied. The aim of our study is to evaluate the cross-sectional association of intradialytic change in BP with cardiac structure and function measured by cardiac MRI in hypertensive HD patients enrolled in the multi-center Blood Pressure in Dialysis (BID) clinical trial.
methodsParticipants in the BID study were categorized into 3 groups based on average change (Δ) in systolic blood pressure (SBP) (post-HD SBP minus pre-HD SBP) during HD over a 1 month period: group 1 - patients with an increase in SBP ≥ 10mm Hg during HD (IDH); group 2 -patients with SBP decrease of greater ≥10mm Hg during HD; group 3 - patients with SBP increase or decrease by < 10mm Hg during HD. LVM index (LVMI) was measured using cardiac MRI, which were centrally read. Baseline characteristics were compared in the 3 groups and multivariable regression models were fitted for the adjusted association of IDH with LVMI.
resultsAmong the 80 participants, 7 (8.8%) had IDH and had average Δ SBP 17.0 ± 10.1 mmHg during HD. Patients with IDH were less likely to be diabetic, had lower pre-dialysis SBP and lower percent interdialytic weight gain as compared to the other 2 groups (p=0.02, p< 0.001 and p=0.02 respectively). In multivariable regression analyses, IDH was significantly associated with LVMI (adjusted mean difference relative to SBP decreased group [95% confidence interval (CI)] = 12.5 [3.6, 21.5], p=0.01) after adjusting for age, sex, diabetes, IDWG%, pre-HD SBP and beta blocker use. Every 1 mm rise in ΔSBP during HD was associated with 0.2 g/m2 increase in LVMI in adjusted models (p=0.04).
conclusionIDH is independently associated with higher LVMI in hypertensive HD patients and may contribute to increased cardiovascular events.
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