Evidence map›Paper›PMID 29870146›Full record

SynthesisPediatric pulmonology2018

Predictors of repeated acute hospital attendance for asthma in children: A systematic review and meta-analysis.

Cristina Ardura-Garcia, Marie Stolbrink, Seher Zaidi, Philip J Cooper, John D Blakey

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Pediatric pulmonology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 5 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
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  5. Pooled it
  6. Article
  7. Review
  8. Article
  9. Article
  10. School-supervised Asthma Therapy is Associated with Improved Long-Term Asthma Outcomes for Underrepresented Minority Children.The Journal of school nursing : the official publication of the National Association of School Nurses · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Medication Adherence in Children with Asthma.Patient preference and adherence · 2024
    Review
  15. Review
  16. Prediction of Asthma Exacerbations in Children.Journal of personalized medicine · 2023
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Cristina Ardura-GarciaLiverpool School of Tropical Medicine, Liverpool, UK.ORCID 0000-0001-7924-518X
Marie StolbrinkLiverpool School of Tropical Medicine, Liverpool, UK.
Seher ZaidiLiverpool School of Tropical Medicine, Liverpool, UK.
Philip J CooperFacultad de Ciencias Medicas, de la Salud y la Vida, Universidad Internacional del Ecuador, Quito, Ecuador.
John D BlakeyRespiratory Medicine, Royal Liverpool Hospital, Liverpool, UK.
Liverpool School of Tropical Medicine · GBSt George's, University of London · GBUniversity of Liverpool · GB

Funding

Wellcome TrustWellcome Trust 099938/B/12/Z
6 · The paper itself

Abstract

backgroundAsthma attacks are common and have significant physical, psychological, and financial consequences. Improving the assessment of a child's risk of subsequent asthma attacks could support front-line clinicians' decisions on augmenting chronic treatment or specialist referral. We aimed to identify predictors for emergency department (ED) or hospital readmission for asthma from the published literature.

methodsWe searched MEDLINE, EMBASE, AMED, PsycINFO, and CINAHL with no language, location, or time restrictions. We retrieved observational studies and randomized controlled trials (RCT) assessing factors (personal and family history, and biomarkers) associated with the risk of ED re-attendance or hospital readmission for acute childhood asthma.

resultsThree RCTs and 33 observational studies were included, 31 from Anglophone countries and none from Asia or Africa. There was an unclear or high risk of bias in 14 of the studies, including 2 of the RCTs. Previous history of emergency or hospital admissions for asthma, younger age, African-American ethnicity, and low socioeconomic status increased risk of subsequent ED and hospital readmissions for acute asthma. Female sex and concomitant allergic diseases also predicted hospital readmission.

conclusionDespite the global importance of this issue, there are relatively few high quality studies or studies from outside North America. Factors other than symptoms are associated with the risk of emergency re-attendance for acute asthma among children. Further research is required to better quantify the risk of future attacks and to assess the role of commonly used biomarkers.

Indexed as

AdolescentAsthmaChildChild, PreschoolEmergency Service, HospitalFemaleHospitalizationHumansInfantInfant, NewbornMaleNorth AmericaObservational Studies as TopicPatient ReadmissionRandomized Controlled Trials as TopicRisk FactorsTobacco Smoke Pollutionasthma attacksemergency departmentfuture riskhospital admissionpaediatric asthma

Identifiers

PMID29870146
PMCPMC6175073
OpenAlexW2806398284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.