ArticleIntegrated environmental assessment and management2018
Incorporating Suborganismal Processes into Dynamic Energy Budget Models for Ecological Risk Assessment.
Article in Integrated environmental assessment and management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- A Systems Approach to Homeostasis: What Euryhaline Fish Teach Us About Organismal Stress Responses.Integrative and comparative biology · 2025Article
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- Key challenges and developments in wildlife ecological risk assessment: Problem formulation.Integrated environmental assessment and management · 2024Review
- Towards Precision Ecotoxicology: Leveraging Evolutionary Conservation of Pharmaceutical and Personal Care Product Targets to Understand Adverse Outcomes Across Species and Life Stages.Environmental toxicology and chemistry · 2024Review
- The consequences of sea lamprey parasitism on lake trout energy budgets.Conservation physiology · 2023Article
- Linking freshwater ecotoxicity to damage on ecosystem services in life cycle assessment.Environment international · 2023Review
- Explicit Consideration of Temperature Improves Predictions of Toxicokinetic-Toxicodynamic Models for Flupyradifurone and Imidacloprid inEnvironmental science & technology · 2022Article
- DEVELOPING INTEGRAL PROJECTION MODELS FOR ECOTOXICOLOGY.Ecological modelling · 2022Article
- Assessing Fish Immunotoxicity by Means ofFrontiers in immunology · 2022Review
- Timescale separation and models of symbiosis: state space reduction, multiple attractors and initialization.Conservation physiology · 2022Article
- Mode of action evaluation for reduced reproduction in Daphnia pulex exposed to the insensitive munition, 1-methyl-3-nitro-1-nitroguanidine (MeNQ).Ecotoxicology (London, England) · 2021Article
- P-glycoprotein induction and its energetic costs in rainbow trout (Oncorhynchus mykiss).Fish physiology and biochemistry · 2021Article
- Integrating Exposure and Effect Distributions with the Ecotoxicity Risk Calculator: Case Studies with Crop Protection Products.Integrated environmental assessment and management · 2021Article
- The role of Dynamic Energy Budgets in conservation physiology.Conservation physiology · 2021Article
- Ecotoxico-lipidomics: An emerging concept to understand chemical-metabolic relationships in comparative fish models.Comparative biochemistry and physiology. Part D, Genomics & proteomics · 2020Review
- Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment.Environmental toxicology and chemistry · 2019Review
- Toward Sustainable Environmental Quality: Priority Research Questions for North America.Environmental toxicology and chemistry · 2019Review
- Applying ecosystem services for pre-market environmental risk assessments of regulated stressors.EFSA journal. European Food Safety Authority · 2019Article
- High-throughput screening and environmental risk assessment: State of the science and emerging applications.Environmental toxicology and chemistry · 2019Review
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
A working group at the National Institute for Mathematical and Biological Synthesis (NIMBioS) explored the feasibility of integrating 2 complementary approaches relevant to ecological risk assessment. Adverse outcome pathway (AOP) models provide "bottom-up" mechanisms to predict specific toxicological effects that could affect an individual's ability to grow, reproduce, and/or survive from a molecular initiating event. Dynamic energy budget (DEB) models offer a "top-down" approach that reverse engineers stressor effects on growth, reproduction, and/or survival into modular characterizations related to the acquisition and processing of energy resources. Thus, AOP models quantify linkages between measurable molecular, cellular, or organ-level events, but they do not offer an explicit route to integratively characterize stressor effects at higher levels of organization. While DEB models provide the inherent basis to link effects on individuals to those at the population and ecosystem levels, their use of abstract variables obscures mechanistic connections to suborganismal biology. To take advantage of both approaches, we developed a conceptual model to link DEB and AOP models by interpreting AOP key events as measures of damage-inducing processes affecting DEB variables and rates. We report on the type and structure of data that are generated for AOP models that may also be useful for DEB models. We also report on case studies under development that merge information collected for AOPs with DEB models and highlight some of the challenges. Finally, we discuss how the linkage of these 2 approaches can improve ecological risk assessment, with possibilities for progress in predicting population responses to toxicant exposures within realistic environments. Integr Environ Assess Manag 2018;14:615-624. © 2018 SETAC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.