Evidence map›Paper›PMID 29870064›Full record

ArticleBiometrics2018

Time-dynamic profiling with application to hospital readmission among patients on dialysis.

Jason P Estes, Danh V Nguyen, Yanjun Chen, Lorien S Dalrymple, Connie M Rhee, Kamyar Kalantar-Zadeh, Damla Şentürk

Abstract read
In one paragraph

Article in Biometrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  5. Limitations of the Inter-Unit Reliability: A Set of Practical Examples.Health services & outcomes research methodology · 2024
    Article
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  7. Competing Risk Modeling with Bivariate Varying Coefficients to Understand the Dynamic Impact of COVID-19.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Analysis of hospital readmissions with competing risks.Statistical methods in medical research · 2022
    Article
  12. MEASURING PERFORMANCE FOR END-OF-LIFE CARE.The annals of applied statistics · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Fixed Effects High-Dimensional Profiling Models in Low Information Context.International journal of statistics in medical research · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jason P EstesDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, U.S.A.ORCID 0000-0003-0639-1121
Danh V NguyenDepartment of Medicine, University of California, Irvine, Orange, California 92868, U.S.A.
Yanjun ChenInstitute for Clinical and Translational Science, Irvine, California 92697, U.S.A.
Lorien S DalrympleDepartment of Medicine, University of California Davis, Sacramento, California 95817, U.S.A.
Connie M RheeDepartment of Medicine, University of California, Irvine, Orange, California 92868, U.S.A.
Kamyar Kalantar-ZadehDepartment of Medicine, University of California, Irvine, Orange, California 92868, U.S.A.
Damla ŞentürkDepartment of Biostatistics, University of California, Los Angeles, California 90095, U.S.A.ORCID 0000-0002-7619-5428

Funding

Multilevel Time-Dynamic Modeling of Hospitalization and Survival in Patients on DialysisR01DK092232 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KURUM, ESRA, NGUYEN, DANH V · 2011 to 2025
$4.9M
Hypothyroidism, Cardiovascular Health, and Survival in Kidney DiseaseK23DK102903 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI RHEE, CONNIE MEEYOUNG · 2014 to 2018
$955k
NIDDK NIH HHS K23 DK102903NIDDK NIH HHS R01 DK092232
6 · The paper itself

Abstract

Standard profiling analysis aims to evaluate medical providers, such as hospitals, nursing homes, or dialysis facilities, with respect to a patient outcome. The outcome, for instance, may be mortality, medical complications, or 30-day (unplanned) hospital readmission. Profiling analysis involves regression modeling of a patient outcome, adjusting for patient health status at baseline, and comparing each provider's outcome rate (e.g., 30-day readmission rate) to a normative standard (e.g., national "average"). Profiling methods exist mostly for non time-varying patient outcomes. However, for patients on dialysis, a unique population which requires continuous medical care, methodologies to monitor patient outcomes continuously over time are particularly relevant. Thus, we introduce a novel time-dynamic profiling (TDP) approach to assess the time-varying 30-day readmission rate. TDP is used to estimate, for the first time, the risk-standardized time-dynamic 30-day hospital readmission rate, throughout the time period that patients are on dialysis. We develop the framework for TDP by introducing the standardized dynamic readmission ratio as a function of time and a multilevel varying coefficient model with facility-specific time-varying effects. We propose estimation and inference procedures tailored to the problem of TDP and to overcome the challenge of high-dimensional parameters when examining thousands of dialysis facilities.

Indexed as

BiometryHumansOutcome Assessment, Health CarePatient ReadmissionRetinal PerforationsRisk FactorsTime FactorsEnd-stage renal diseaseHospital readmissionMultilevel varying coefficient modelsProfiling of medical care providersUnited States Renal Data System

Identifiers

PMID29870064
PMCPMC6296887

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.