Evidence map›Paper›PMID 29869981›Full record

ArticleeLife2018

Diversification of heart progenitor cells by EGF signaling and differential modulation of ETS protein activity.

Benjamin Schwarz, Dominik Hollfelder, Katharina Scharf, Leonie Hartmann, Ingolf Reim

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Adipose Dicer-1 modulates systemic insulin signaling and longevity via a miR-8-Aop-Dilp6 axis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin SchwarzDepartment of Biology, Division of Developmental Biology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.
Dominik HollfelderDepartment of Biology, Division of Developmental Biology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.
Katharina ScharfDepartment of Biology, Division of Developmental Biology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.
Leonie HartmannDepartment of Biology, Division of Developmental Biology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.
Ingolf ReimDepartment of Biology, Division of Developmental Biology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.ORCID http://orcid.org/0000-0001-8069-5532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For coordinated circulation, vertebrate and invertebrate hearts require stereotyped arrangements of diverse cell populations. This study explores the process of cardiac cell diversification in the

Indexed as

Signal TransductionAnimalsAnimals, Genetically ModifiedCells, CulturedDrosophila melanogasterEmbryo, NonmammalianEpidermal Growth FactorGene Expression Regulation, DevelopmentalHeartProto-Oncogene Protein c-ets-1Stem CellsEpidermal Growth FactorProto-Oncogene Protein c-ets-1cardiac cell specificationdevelopmental biologyD. melanogasterepidermal growth factor signalingETS transcription factorsSAM domain factorsseven-up/COUP-TFIIT-box factors

Identifiers

PMID29869981
PMCPMC6033539

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.