Evidence map›Paper›PMID 29869917›Full record

ReviewThe British journal of radiology2018

Obesity, metabolic disease and the pancreas-Quantitative imaging of pancreatic fat.

Naomi S Sakai, Stuart A Taylor, Manil D Chouhan

Abstract readReview
In one paragraph

Review in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Naomi S Sakai1 UCL Centre for Medical Imaging, Division of Medicine, University College London , London , UK.
Stuart A Taylor1 UCL Centre for Medical Imaging, Division of Medicine, University College London , London , UK.
Manil D Chouhan1 UCL Centre for Medical Imaging, Division of Medicine, University College London , London , UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between pancreatic fat, obesity and metabolic disease is well-documented, and although a potentially exciting target for novel therapies, remains poorly understood. Non-invasive quantitative imaging-derived biomarkers can provide insights into pathophysiology and potentially provide robust trial endpoints for development of new treatments. In this review, we provide an overview of the pathophysiology of non-alcoholic fatty pancreas disease and associations with metabolic factors, obesity and diabetes. We then explore approaches to pancreatic fat quantification using ultrasound, CT and MRI, reviewing the strengths, limitations and current published evidence in the assessment of pancreatic fat. Finally, we explore the broader challenges of pancreatic fat quantification as we move toward translating these methods into the clinical setting.

Indexed as

Adipose TissueBody CompositionHumansMagnetic Resonance ImagingMetabolic SyndromeObesityPancreasPancreatic DiseasesTomography, X-Ray Computed

Identifiers

PMID29869917
PMCPMC6223168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.