ArticleInternational urology and nephrology2018
Association between preoperative hydration status and acute kidney injury in patients managed surgically for kidney tumours.
Article in International urology and nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement.British journal of anaesthesia · 2025Pooled it
- Association of intraoperative hypotension with postoperative morbidity and mortality: systematic review and meta-analysis.BJS open · 2021Pooled it
- Trial
- Volume kinetic analysis of fluid retention after induction of general anesthesia.BMC anesthesiology · 2020Trial
- Effects of concentrated urine on complications and plasma creatinine: a prospective study in elective non-cardiac surgery patients.Frontiers in medicine · 2025Article
- Development and validation of a risk prediction model for perioperative acute kidney injury in non-cardiac and non-urological surgery patients: a retrospective cohort study.Frontiers in physiology · 2025Article
- Review
- Review
- The association between modifiable perioperative parameters and renal function after nephrectomy.BJU international · 2022Article
- [Preoperative fluid fasting : Establishment of a liberal fluid regimen using fasting cards].Der Anaesthesist · 2021Article
- [Comments on the updated German S3 guidelines on intravascular volume therapy in adults].Der Anaesthesist · 2021Review
- Preoperative Concentrated Urine Increases the Incidence of Plasma Creatinine Elevation After Major Surgery.Frontiers in medicine · 2021Article
- Acute Kidney Injury in Oncology Patients.Journal of Cancer · 2020Article
- New-onset renal impairment following radical nephrectomy for renal cell carcinoma: a retrospective cohort study of clinical, intraoperative, and postoperative risk factors.Therapeutic advances in urologyArticle
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to investigate whether preoperative dehydration and intraoperative hypotension were associated with postoperative acute kidney injury in patients managed surgically for kidney tumours.
methodsA retrospective analysis of 184 patients who underwent nephrectomy at a single centre was performed, investigating associations between acute kidney injury after nephrectomy, and both intraoperative hypotension and preoperative hydration/volume status. Intraoperative hypotension was defined as mean arterial pressure < 60 mmHg for ≥ 5 min. Urine conductivity was evaluated as a surrogate measure of preoperative hydration (euhydrated < 15 mS/cm; mildly dehydrated 15-20 mS/cm; dehydrated > 20 mS/cm). Multivariable logistic regression was used to evaluate associations between exposures and the primary outcome, with adjustment made for potential confounders.
resultsPatients who were dehydrated and mildly dehydrated had an increased risk of acute kidney injury (adjusted odds ratio [aOR] 4.1, 95% CI 1.3-13.5; and aOR 2.4, 95% CI 1.1-5.3, respectively) compared with euhydrated patients (p = 0.009). Surgical approach appeared to modify this effect, where dehydrated patients undergoing laparoscopic surgery were most likely to develop acute kidney injury, compared with patients managed using an open approach. Intraoperative hypotension was not associated with acute kidney injury.
conclusionPreoperative dehydration may be associated with postoperative acute kidney injury. Avoiding dehydration in the preoperative period may be advisable, and adherence to international evidence-based guidelines on preoperative fasting is recommended.
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