SynthesisEuropean journal of applied physiology2018
Left ventricular function and mechanics following prolonged endurance exercise: an update and meta-analysis with insights from novel techniques.
Synthesis in European journal of applied physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Influence of Endurance Training, High-Intensity Interval Training, and Acute Exercise on Left Ventricular Mechanics: A Systematic Review.Journal of clinical medicine · 2025Review
- Adaptive Changes in Endurance Athletes: A Review of Molecular, Echocardiographic and Electrocardiographic Findings.International journal of molecular sciences · 2025Review
- Cardiac Fatigue in Male Athletes with Exercise-Induced Pulmonary Impairments After a Very Long-Distance Triathlon.Sports medicine (Auckland, N.Z.) · 2025Article
- Olympic distance duathlon and cardiac performance in highly-trained triathletes.Physiological reports · 2024Article
- A new perspective on cardiovascular function and dysfunction during endurance exercise: identifying the primary cause of cardiovascular risk.Biology of sport · 2024Article
- Lifelong physiology of a former marathon world-record holder: the pros and cons of extreme cardiac remodeling.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Exercise-Induced Cardiac Troponin I Elevation Is Associated With Regional Alterations in Left Ventricular Strain in High-Troponin Responders.Journal of the American Heart Association · 2024Observational
- Limits of Ultra: Towards an Interdisciplinary Understanding of Ultra-Endurance Running Performance.Sports medicine (Auckland, N.Z.) · 2024Review
- Assessment of right ventricular structure and systolic function in amateur marathon runners using three-dimensional speckle tracking echocardiography.The international journal of cardiovascular imaging · 2023Article
- May Strenuous Endurance Sports Activity Damage the Cardiovascular System of Healthy Athletes? A Narrative Review.Journal of cardiovascular development and disease · 2022Review
- Changes in cardiac function following a speed ascent to the top of Europe at 4808 m.European journal of applied physiology · 2022Article
- Impact of long-lasting moderate-intensity stage cycling event on cardiac function in young female athletes: A case study.PloS one · 2022Article
- Myocardial inefficiency is an early indicator of exercise-induced myocardial fatigue.Frontiers in cardiovascular medicine · 2022Article
- Exercise-Induced Cardiac Fatigue in Soldiers Assessed by Echocardiography.Frontiers in cardiovascular medicine · 2021Article
- Factors Related to Cardiac Troponin T Increase after Participation in a 100 Km Ultra-Marathon.Diagnostics (Basel, Switzerland) · 2020Article
- The strain and strain rate imaging paradox in echocardiography: overabundant literature in the last two decades but still uncertain clinical utility in an individual case.Archives of medical sciences. Atherosclerotic diseases · 2020Article
- Alterations in Cardiac Function Following Endurance Exercise Are Not Duration Dependent.Frontiers in physiology · 2020Article
- Neuromuscular fatigue during whole body exercise.Current opinion in physiology · 2019Article
- Effect of ingesting carbohydrate only or carbohydrate plus casein protein hydrolysate during a multiday cycling race on left ventricular function, plasma volume expansion and cardiac biomarkers.European journal of applied physiology · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe cardiac consequences of undertaking endurance exercise are the topic of recent debate. The purpose of this review is to provide an update on a growing body of literature, focusing on left ventricular (LV) function following prolonged endurance exercise over 2 h in duration which have employed novel techniques, including myocardial speckle tracking, to provide a more comprehensive global and regional assessment of LV mechanics.
methodsProspective studies were filtered independently following a pre-set criteria, resulting in the inclusion of 27 studies in the analyses. A random-effects meta-analysis was used to determine the weighted mean difference and 95% confidence intervals (CI) of LV functional and mechanical data from pre-to-post-exercise. Narrative commentary was also provided where volume of available evidence precluded meta-analysis.
resultsA significant overall reduction in LV longitudinal strain (Ɛ) n = 22 (- 18 ± 1 to - 17 ± 1%; effect size (d) - 9: - 1 to - 0.5%), strain rate n = 10 (SR; d - 0.9: - 0.1.3 to - 0.5 l/s) and twist n = 5 (11.9 ± 2.2 to 8.7 ± 2.2°, d - 1: - 1.6 to - 0.3°) was observed following strenuous endurance exercise (range 120-1740 min) (P < 0.01). A smaller number of studies (n = 4) also reported a non-significant reduction in global circumferential and radial Ɛ (P > 0.05).
conclusionThe meta-analysis and narrative commentary demonstrated that a reduction in LV function and mechanics is evident following prolonged endurance exercise. The mechanism(s) responsible for these changes are complex and likely multi-factorial in nature and may be linked to right and left ventricular interaction.
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