Evidence map›Paper›PMID 29869539›Full record

ReviewDrug delivery2018

Nanoparticle drug delivery systems: an excellent carrier for tumor peptide vaccines.

Jiemin Wang, Xiongbin Hu, Daxiong Xiang

Abstract readReview
In one paragraph

Review in Drug delivery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
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  10. An Overview of In Vitro Assays ofDiagnostics (Basel, Switzerland) · 2023
    Review
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  12. Review
  13. Review
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  18. Review
  19. Current Prospects in Peptide-Based Subunit Nanovaccines.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiemin Wanga Department of Pharmacy , Second Xiangya Hospital Central South University , Changsha , Hunan Province , China.ORCID http://orcid.org/0000-0003-3285-5663
Xiongbin Hua Department of Pharmacy , Second Xiangya Hospital Central South University , Changsha , Hunan Province , China.
Daxiong Xianga Department of Pharmacy , Second Xiangya Hospital Central South University , Changsha , Hunan Province , China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past 40 years, the nanoparticle drug delivery system for tumor peptide vaccines has been widely studied which also reached a splendid result. Nanomaterial can enhance the targeting of vaccines, help vaccines enter the cells and trigger immune response by themselves. They also help in increasing cellular uptake, improving permeability and efficacy. Currently, several categories of nanopreparation, such as liposome, polymeric micelle, polymeric nanoparticle, gold nanoparticle and so on, are proved that they are appropriate for peptide vaccines. This review we discussed the possible mechanisms of nanomaterial's action on the regulation of immunological functions and several major applications of this advanced drug delivery system for tumor peptide vaccine.

Indexed as

AnimalsCancer VaccinesDrug CarriersDrug Delivery SystemsHumansNanoparticlesPeptidesVaccines, SubunitCancer VaccinesDrug CarriersPeptidesVaccines, SubunitDrug delivery systemimmunotherapynanopeptide vaccinetumor

Identifiers

PMID29869539
PMCPMC6058474

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.