Evidence map›Paper›PMID 29869394›Full record

ArticleJournal of biophotonics2018

Optical study of chemotherapy efficiency in cancer treatment via intracellular structural disorder analysis using partial wave spectroscopy.

Huda M Almabadi, Prashanth K B Nagesh, Peeyush Sahay, Shiva Bhandari, Eugene C Eckstein, Meena Jaggi, Subhash C Chauhan, Murali M Yallapu, Prabhakar Pradhan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biophotonics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Spectroscopic Study onMolecules (Basel, Switzerland) · 2020
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huda M AlmabadiDepartment of Physics and Materials Science, BioNanoPhotonics Laboratory, University of Memphis, Memphis, Tennessee.
Prashanth K B NageshDepartment of Pharmaceutical Sciences and the Center for Cancer Research, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee.
Peeyush SahayDepartment of Physics and Materials Science, BioNanoPhotonics Laboratory, University of Memphis, Memphis, Tennessee.
Shiva BhandariDepartment of Physics and Materials Science, BioNanoPhotonics Laboratory, University of Memphis, Memphis, Tennessee.
Eugene C EcksteinBiomedical Engineering, University of Memphis, Memphis, Tennessee.
Meena JaggiDepartment of Pharmaceutical Sciences and the Center for Cancer Research, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee.
Subhash C ChauhanDepartment of Pharmaceutical Sciences and the Center for Cancer Research, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee.
Murali M YallapuDepartment of Pharmaceutical Sciences and the Center for Cancer Research, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee.
Prabhakar PradhanDepartment of Physics and Materials Science, BioNanoPhotonics Laboratory, University of Memphis, Memphis, Tennessee.ORCID 0000-0002-1601-3506

Funding

Mechanisms of Light Scattering in Living TissuesR01EB003682 · NIBIB · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM, PRADHAN, PRABHAKAR · 2005 to 2013
$2.2M
miR-205 Nanoparticle system circumvents docetaxel resistance in prostate cancerSC1GM139727 · NIGMS · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI YALLAPU, MURALI MOHAN · 2021 to 2024
$1.5M
High-throughput molecular-specific cell nanocytology for cancer screeningR01EB016983 · NIBIB · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM, SUBRAMANIAN, HARIHARAN · 2013 to 2016
$1.3M
PSMA Targeted Docetaxel Loaded Magnetic Nanoparticles for Prostate Cancer TherapyK22CA174841 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI YALLAPU, MURALI MOHAN · 2015 to 2017
$485k
Targeted Nano-Chemosensitization of Breast CancersR15CA213232 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI KUMAR, SANTOSH · 2017 to 2017
$440k
NCI NIH HHS K22 CA174841NCI NIH HHS R15 CA213232NIBIB NIH HHS R01 EB003682NIBIB NIH HHS R01 EB016983NIGMS NIH HHS SC1 GM139727NIH HHS NIH K22 CA1748841NIH HHS NIH R15 CA213232NIH HHS R01EB003682NIH HHS R01EB016983
6 · The paper itself

Abstract

As cancer progresses, macromolecules, such as DNA, RNA or lipids, inside cells undergo spatial structural rearrangements and alterations. Mesoscopic light transport-based optical partial wave spectroscopy (PWS) was recently introduced to quantify changes in the nanoscale structural disorder in biological cells. The PWS measurement is performed using a parameter termed as "disorder strength" (L

Indexed as

Spectrum AnalysisCell Line, TumorHumansIntracellular SpaceMaleProstatic NeoplasmsTreatment Outcomebiophotonicscancerchemoresistancelight transportoptical disorder

Identifiers

PMID29869394
PMCPMC13459130

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.