Evidence map›Paper›PMID 29869099›Full record

ArticleCellular and molecular neurobiology2018

Permanent Photodynamic Cholecystokinin 1 Receptor Activation: Dimer-to-Monomer Conversion.

Wen Yi Jiang, Yuan Li, Zhi Ying Li, Zong Jie Cui

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. To activate NAD(P)H oxidase with a brief pulse of photodynamic action.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  4. Activation of the G protein-coupled sulfakinin receptor inhibits blood meal intake in the mosquito Aedes aegypti.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wen Yi JiangInstitute of Cell Biology, Beijing Normal University, Beijing, 100875, China.
Yuan LiInstitute of Cell Biology, Beijing Normal University, Beijing, 100875, China.
Zhi Ying LiInstitute of Cell Biology, Beijing Normal University, Beijing, 100875, China.
Zong Jie CuiInstitute of Cell Biology, Beijing Normal University, Beijing, 100875, China. zjcui@bnu.edu.cn.ORCID http://orcid.org/0000-0003-4252-4876
Beijing Normal University · CN

Funding

The Ministry of Science and Technology of China 2011CB809101The Natural Science Foundation of China 31670856, 31270892
6 · The paper itself

Abstract

The G protein-coupled cholecystokinin 1 receptor (CCK1R) is activated permanently by type II photodynamic action (i.e., by singlet oxygen) in the freshly isolated rat pancreatic acini, in contrast to reversible activation by CCK. But how CCK1R is photodynamically activated is not known. Therefore, in the present work, we subjected membrane proteins extracted from isolated rat pancreatic acini to photodynamic action with photosensitiser sulphonated aluminium phthalocyanine (SALPC), and used reducing gel electrophoresis and Western blot to detect possible changes in CCK1R oligomerization status. Photodynamic action (SALPC 1 µM, light 36.7 mW cm

Indexed as

DimerizationAnimalsCholecystokininIndolesIsoindolesMaleMembrane ProteinsMonomeric GTP-Binding ProteinsRats, Sprague-DawleyReceptors, CholecystokininSignal TransductionCholecystokininIndolesIsoindolesMembrane ProteinsMonomeric GTP-Binding ProteinsphthalocyanineReceptors, CholecystokininCholecystokinin 1 receptor (CCK1R)G protein-coupled receptor activated by singlet oxygen (GPCR-ABSO)Permanent activationPhotodynamic pharmacology

Identifiers

PMID29869099
PMCPMC11482018
OpenAlexW2805166639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.