ReviewSports medicine (Auckland, N.Z.)2018
Exercise-Derived Microvesicles: A Review of the Literature.
Review in Sports medicine (Auckland, N.Z.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exercise and Circulating Microparticles in Healthy Subjects.Journal of cardiovascular translational research · 2021Pooled it
- Individuals with controlled hypertension show endothelial integrity following a bout of moderate-intensity exercise: randomized clinical trial.Scientific reports · 2021Trial
- Effects of exercise‑derived extracellular vesicles: Epigenetic regulatory mechanisms and protective roles (Review).International journal of molecular medicine · 2026Review
- Exercise and its beneficial impacts on mood disorders and neurodegeneration: a novel mechanistic perspective of the exosomes involvement.Molecular and cellular biochemistry · 2025Review
- Mesenchymal stem cell-derived extracellular vesicles in periodontal bone repair.Journal of molecular medicine (Berlin, Germany) · 2025Review
- The Role of Exercise in Regulating the Generation of Extracellular Vesicles in Cardiovascular Diseases.Reviews in cardiovascular medicine · 2024Review
- Biomarkers ofFrontiers in veterinary science · 2024Article
- Cell-Free miRNAs as Non-Invasive Biomarkers in Brain Tumors.Diagnostics (Basel, Switzerland) · 2023Review
- Effects of Exercise Training on Circulating Biomarkers of Endothelial Function in Pulmonary Arterial Hypertension.Biomedicines · 2023Article
- Exercise Improves Metabolism and Alleviates Atherosclerosis via Muscle-Derived Extracellular Vesicles.Aging and disease · 2023Article
- Effects of Exercise on Circulating Extracellular Vesicles in Cardiovascular Disease.Advances in experimental medicine and biology · 2023Article
- Article
- Prophylactic exercise-derived circulating exosomal miR-125a-5p promotes endogenous revascularization after hindlimb ischemia by targeting endothelin converting enzyme 1.Frontiers in cardiovascular medicine · 2022Article
- Review
- Circulating Extracellular Vesicles: The Missing Link between Physical Exercise and Depression Management?International journal of molecular sciences · 2021Review
- Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Exosome: A New Player in Translational Nanomedicine.Journal of clinical medicine · 2020Review
- Effects of an acute bout of exercise on circulating extracellular vesicles: tissue-, sex-, and BMI-related differences.International journal of obesity (2005) · 2020Article
- Extracellular Vesicles and Exosomes: Insights From Exercise Science.Frontiers in physiology · 2020Review
- Considerations for the Analysis of Small Extracellular Vesicles in Physical Exercise.Frontiers in physiology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Initially suggested as simple cell debris, cell-derived microvesicles (MVs) have now gained acceptance as recognized players in cellular communication and physiology. Shed by most, and perhaps all, human cells, these tiny lipid-membrane vesicles carry bioactive agents, such as proteins, lipids and microRNA from their cell source, and are produced under orchestrated events in response to a myriad of stimuli. Physical exercise introduces systemic physiological challenges capable of acutely disrupting cell homeostasis and stimulating the release of MVs into the circulation. The novel and promising field of exercise-derived MVs is expanding quickly, and the following work provides a review of the influence of exercise on circulating MVs, considering both acute and chronic aspects of exercise and training. Potential effects of the MV response to exercise are highlighted and future directions suggested as exercise and sports sciences extend the realm of extracellular vesicles.
Indexed as
Identifiers
29868992What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.