Evidence map›Paper›PMID 29868983›Full record

ArticleNeurochemical research2018

Lead Neurotoxicity on Human Neuroblastoma Cell Line SH-SY5Y is Mediated via Transcription Factor EGR1/Zif268 Induced Disrupted in Scherophernia-1 Activation.

Yuanyuan You, Bo Peng, Songbin Ben, Weijian Hou, Liguang Sun, Wei Jiang

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. EDTA Chelation Therapy for the Treatment of Neurotoxicity.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yuanyuan YouDepartment of Genetic, Shenyang Maternity and Child Health Hospital, Shenyang, People's Republic of China.
Bo PengOutpatient Department, China Medical University, Shenyang, People's Republic of China.
Songbin BenLife Science College, Liaoning University, Shenyang, People's Republic of China.
Weijian HouDepartment of Tissue Engineering, China Medical University, Shenyang, People's Republic of China.
Liguang SunDepartment of Biochemical and Molecular Biology, China Medical University, No. 77 of Puhe Road, Beixin District, Shenyang, 110127, Liaoning, People's Republic of China. liguangsun@hotmail.com.
Wei JiangDepartment of Biological Science, Liaoning Academy of Analytical Sciences, Shenyang, People's Republic of China.
China Medical University · CNLiaoning University · CNShenyang Academy of Environmental Sciences (China) · CNShenyang Maternity and Child Health Hospital

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lead (Pb

Indexed as

Cell Line, TumorCell SurvivalDose-Response Relationship, DrugEarly Growth Response Protein 1HumansNerve Tissue ProteinsNeuroblastomaOrganometallic CompoundsTranscription FactorsDISC1 protein, humanEarly Growth Response Protein 1EGR1 protein, humanlead acetateNerve Tissue ProteinsOrganometallic CompoundsTranscription FactorsDisrupted in scherophernia-1Early growth response gene 1Lead injuryNeurotoxicityPromoter

Identifiers

PMID29868983
OpenAlexW2805202476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.