Evidence map›Paper›PMID 29868643›Full record

ArticleScience advances2018

Evidence of link between quorum sensing and sugar metabolism in

Jung-Hye Ha, Pricila Hauk, Kun Cho, Yumi Eo, Xiaochu Ma, Kristina Stephens, Soyoung Cha, Migyeong Jeong, Jeong-Yong Suh, Herman O Sintim and 2 more

Abstract read
In one paragraph

Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Conversations in the Gut: The Role of Quorum Sensing in Normobiosis.International journal of molecular sciences · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jung-Hye HaProtein Structure Research Group, Korea Basic Science Institute, 162 Yeongudanji-ro, Ochang-eup, Cheongju-si, Chungcheongbuk-do 28119, South Korea.ORCID 0000-0001-9139-767X
Pricila HaukInstitute for Bioscience and Biotechnology Research, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0002-4761-1920
Kun ChoBiomedical Omics Group, Korea Basic Science Institute, Chungcheongbuk-do 28119, South Korea.ORCID 0000-0003-1154-4065
Yumi EoProtein Structure Research Group, Korea Basic Science Institute, 162 Yeongudanji-ro, Ochang-eup, Cheongju-si, Chungcheongbuk-do 28119, South Korea.
Xiaochu MaDepartment of Chemistry and Institute for Drug Discovery, Purdue University, West Lafayette, IN 47907, USA.
Kristina StephensInstitute for Bioscience and Biotechnology Research, University of Maryland, College Park, MD 20742, USA.
Soyoung ChaProtein Structure Research Group, Korea Basic Science Institute, 162 Yeongudanji-ro, Ochang-eup, Cheongju-si, Chungcheongbuk-do 28119, South Korea.ORCID 0000-0002-4692-8117
Migyeong JeongDepartment of Agricultural Biotechnology, Seoul National University, Seoul 08826, South Korea.
Jeong-Yong SuhDepartment of Agricultural Biotechnology, Seoul National University, Seoul 08826, South Korea.ORCID 0000-0001-8720-3844
Herman O SintimDepartment of Chemistry and Institute for Drug Discovery, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-2280-9359
William E BentleyInstitute for Bioscience and Biotechnology Research, University of Maryland, College Park, MD 20742, USA.
Kyoung-Seok RyuProtein Structure Research Group, Korea Basic Science Institute, 162 Yeongudanji-ro, Ochang-eup, Cheongju-si, Chungcheongbuk-do 28119, South Korea.ORCID 0000-0002-8422-6669

Funding

Training in Host-pathogens interactionsT32AI089621 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI LEE, VINCENT T, MCIVER, KEVIN S. · 2010 to 2025
$2.1M
Accessing molecular communication via synthetic biology and microelectronics – gut on a chip modelR21EB024102 · NIBIB · UNIV OF MARYLAND, COLLEGE PARK · PI BENTLEY, WILLIAM E. · 2017 to 2018
$412k
NIAID NIH HHS T32 AI089621NIBIB NIH HHS R21 EB024102
6 · The paper itself

Abstract

Quorum sensing (QS), a bacterial process that regulates population-scale behavior, is mediated by small signaling molecules, called autoinducers (AIs), that are secreted and perceived, modulating a "collective" phenotype. Because the autoinducer AI-2 is secreted by a wide variety of bacterial species, its "perception" cues bacterial behavior. This response is mediated by the

Indexed as

Quorum SensingAmino Acid SequenceBacterial ProteinsCarbohydrate MetabolismEnzyme ActivationEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialKineticsModels, MolecularPhosphoenolpyruvate Sugar Phosphotransferase SystemPhosphotransferases (Alcohol Group Acceptor)Promoter Regions, GeneticProtein BindingProtein ConformationRecombinant ProteinsBacterial ProteinsEscherichia coli ProteinsLsrK protein, E coliphosphocarrier protein HPrPhosphoenolpyruvate Sugar Phosphotransferase SystemPhosphotransferases (Alcohol Group Acceptor)Recombinant ProteinsSugars

Identifiers

PMID29868643
PMCPMC5983913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.