Evidence map›Paper›PMID 29868501›Full record

ArticleFrontiers in cellular and infection microbiology2018

The Loss of Expression of a Single Type 3 Effector (CT622) Strongly Reduces

Mathilde M Cossé, Michael L Barta, Derek J Fisher, Lena K Oesterlin, Béatrice Niragire, Stéphanie Perrinet, Gaël A Millot, P Scott Hefty, Agathe Subtil

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Type III Secretion inMicrobiology and molecular biology reviews : MMBR · 2023
    Review
  6. Requirement of GrgA forbioRxiv : the preprint server for biology · 2023
    Article
  7. Review
  8. Review
  9. Advances in genetic manipulation ofFrontiers in immunology · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. TheProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  14. Article
  15. The Putative Type III SecretedFrontiers in microbiology · 2020
    Article
  16. Review
  17. The multiple functions of the numerousMicrobial cell (Graz, Austria) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mathilde M CosséUnité de Biologie Cellulaire de l'Infection Microbienne, Institut Pasteur, Paris, France.
Michael L BartaDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS, United States.
Derek J FisherDepartment of Microbiology, Southern Illinois University, Carbondale, IL, United States.
Lena K OesterlinInstitut Curie, PSL Research University, Centre National de la Recherche Scientifique UMR 144, Molecular Mechanisms of Intracellular Transport, Paris, France.
Béatrice NiragireUnité de Biologie Cellulaire de l'Infection Microbienne, Institut Pasteur, Paris, France.
Stéphanie PerrinetUnité de Biologie Cellulaire de l'Infection Microbienne, Institut Pasteur, Paris, France.
Gaël A MillotInstitut Pasteur-Bioinformatics and Biostatistics Hub-C3BI, USR3756 IP Centre National de la Recherche Scientifique, Paris, France.
P Scott HeftyDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS, United States.
Agathe SubtilUnité de Biologie Cellulaire de l'Infection Microbienne, Institut Pasteur, Paris, France.

Funding

Synthetic Chemical Biology CoreP20GM113117 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI OROZCO, ROBIN C. · 2016 to 2025
$23.9M
Protein Structure Laboratory P30GM110761 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI HANZLIK, ROBERT P · 2014 to 2018
$5.6M
Regulation of Virulence Gene Expression in ChlamydiaR01AI079083 · NIAID · UNIVERSITY OF KANSAS LAWRENCE · PI HEFTY, P SCOTT · 2010 to 2014
$1.8M
Development of gene inactivation methods for Chlamydia spp.R21AI115238 · NIAID · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI FISHER, DEREK JAMES · 2015 to 2016
$406k
European Research Council 282046NIAID NIH HHS R01 AI079083NIAID NIH HHS R21 AI115238NIGMS NIH HHS P20 GM113117NIGMS NIH HHS P30 GM110761
6 · The paper itself

Abstract

Invasion of epithelial cells by the obligate intracellular bacterium

Indexed as

Antigens, BacterialBacterial ProteinsCell ProliferationChlamydia InfectionsChlamydia trachomatisCloning, MolecularCytoplasmGene Expression ProfilingGene Expression Regulation, BacterialGenes, BacterialHeLa CellsHost-Pathogen InteractionsHumansModels, MolecularProtein ConformationSecretory PathwayAntigens, BacterialBacterial ProteinsType III Secretion Systemschaperone proteinsChlamydia trachomatiseffector proteinsgenetic manipulationhost-pathogen interactionsprenylationstructural biology

Identifiers

PMID29868501
PMCPMC5962693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.