Evidence map›Paper›PMID 29868490›Full record

ArticleFrontiers in cellular and infection microbiology2018

FcpB Is a Surface Filament Protein of the Endoflagellum Required for the Motility of the Spirochete

Elsio A Wunder, Leyla Slamti, David N Suwondo, Kimberley H Gibson, Zhiguo Shang, Charles V Sindelar, Felipe Trajtenberg, Alejandro Buschiazzo, Albert I Ko, Mathieu Picardeau

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Core-sheath coupling controls flagellar curvature and motility inbioRxiv : the preprint server for biology · 2026
    Article
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  11. Review
  12. Review
  13. Article
  14. Escape of TLR5 Recognition byFrontiers in immunology · 2020
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Elsio A WunderDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, United States.
Leyla SlamtiInstitut Pasteur, Biology of Spirochetes Unit, Paris, France.
David N SuwondoDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, United States.
Kimberley H GibsonDepartments of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, United States.
Zhiguo ShangDepartments of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, United States.
Charles V SindelarDepartments of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, United States.
Felipe TrajtenbergInstitut Pasteur de Montevideo, Laboratory of Molecular and Structural Microbiology, Montevideo, Uruguay.
Alejandro BuschiazzoInstitut Pasteur de Montevideo, Laboratory of Molecular and Structural Microbiology, Montevideo, Uruguay.
Albert I KoDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, United States.
Mathieu PicardeauInstitut Pasteur, Biology of Spirochetes Unit, Paris, France.
Yale University · USInstitut Pasteur · FRInstitut Pasteur de Montevideo · UY

Funding

Naturally-Acquired and Vaccine-Mediated Immunity to LeptospirosisR01AI121207 · NIAID · YALE UNIVERSITY · PI KO, ALBERT ICKSANG, REIS, MITERMAYER GALVAO DOS · 2016 to 2020
$6.4M
Disease Determinants of Urban LeptospirosisU01AI088752 · NIAID · YALE UNIVERSITY · PI KO, ALBERT ICKSANG · 2010 to 2014
$3.6M
Natural History of Urban LeptospirosisR01AI052473 · NIAID · YALE UNIVERSITY · PI KO, ALBERT ICKSANG · 2003 to 2013
$2.8M
Ecoepidemiology of leptospirosis in the urban slums of BrazilR01TW009504 · FIC · YALE UNIVERSITY · PI BEGON, MICHAEL, CHILDS, JAMES EMORY · 2012 to 2016
$2.2M
FIC NIH HHS R01 TW009504NIAID NIH HHS R01 AI052473NIAID NIH HHS R01 AI121207NIAID NIH HHS U01 AI088752
6 · The paper itself

Abstract

The spirochete endoflagellum is a unique motility apparatus among bacteria. Despite its critical importance for pathogenesis, the full composition of the flagellum remains to be determined. We have recently reported that FcpA is a novel flagellar protein and a major component of the sheath of the filament of the spirochete

Indexed as

Amino Acid SequenceCell MovementCryoelectron MicroscopyDNA Transposable ElementsFlagellaFlagellinLeptospiraMicroscopy, VideoPhenotypeSequence AlignmentSequence DeletionDNA Transposable ElementsFlagellinflagellaflagellar systemLeptospiramotilityspirochetes

Identifiers

PMID29868490
PMCPMC5953323
OpenAlexW2801880959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.