ArticlePeerJ2018
Antioxidant status of rats' blood and liver affected by sodium selenite and selenium nanoparticles.
Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Antioxidant and Anticancer Activities of Bio-Synthesized Selenium Nanoparticles by Escherichia coli.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- The effect of biogenic selenium nanoparticles (Frontiers in veterinary science · 2025Article
- Photo-physical characterizations and evaluation of in-vitro antioxidant, anti-inflammatory and antidiabetic potentials of green synthesized ackee (Blighia sapida) selenium nano-particles.BMC complementary medicine and therapies · 2024Article
- Antioxidant Response of Maternal and Fetal Rat Liver to Selenium Nanoparticle Supplementation Compared to Sodium Selenite: Sex Differences between Fetuses.Antioxidants (Basel, Switzerland) · 2024Article
- Effect of selenium nanoparticles on the quality and fertility of short-term preserved boar semen.Frontiers in veterinary science · 2023Article
- Toxicological effects of nanoselenium in animals.Journal of animal science and biotechnology · 2022Review
- An In Vitro Evaluation of Selenium Nanoparticles on Osteoblastic Differentiation and Antimicrobial Properties againstNanomaterials (Basel, Switzerland) · 2022Article
- Radiolytic synthesis and characterization of selenium nanoparticles: comparative biosafety evaluation with selenite and ionizing radiation.World journal of microbiology & biotechnology · 2022Article
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- Ameliorative effect of selenium nanoparticles against aluminum chloride-induced hepatorenal toxicity in rats.Environmental science and pollution research international · 2019Article
- Biogenic selenium nanoparticles synthesized byInternational journal of nanomedicine · 2019Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSelenium is an essential element; however, at higher doses, it can be toxic. Therefore, alternative nanotechnological solutions are required to overcome toxicological issues, rather than conventional alternatives. Nanoparticles show new and promising properties that may be able to suppress toxicity while maintaining the positive effects of selenium on an organism. The aim of the experiment was to determine the influence of sodium selenite and selenium nanoparticles (SeNPs) on the antioxidant status of rats.
methodsThe males of the outbreed rat strain Wistar albino were selected as a model organism. Animals were fed different forms of selenium. The control group was given a mixture without selenium addition, whereas other groups were fed a mixture containing sodium selenite, Se-49, and Se-100 SeNPs respectively. The duration of the trial was 30 days.
resultsAnalysis of blood and liver was performed where the concentration of reduced (GSH) and oxidised (GSSG) glutathione, and total selenium content were measured. In the liver, a significant reduction in GSSG was found for all experiment groups. Blood samples showed a significant reduction in GSH and an increase in GSSG. DISCUSSION: These results show that SeNPs may be an alternative to dietary selenium for animal organisms.
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