Evidence map›Paper›PMID 29868124›Full record

ArticleFrontiers in genetics2018

Genetics of Obesity Traits: A Bivariate Genome-Wide Association Analysis.

Yili Wu, Haiping Duan, Xiaocao Tian, Chunsheng Xu, Weijing Wang, Wenjie Jiang, Zengchang Pang, Dongfeng Zhang, Qihua Tan

Abstract read
In one paragraph

Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yili WuDepartment of Epidemiology and Health Statistics, Public Health College, Qingdao University, Qingdao, China.
Haiping DuanDepartment of Epidemiology and Health Statistics, Public Health College, Qingdao University, Qingdao, China.
Xiaocao TianQingdao Municipal Center for Disease Control and Prevention, Qingdao, China.
Chunsheng XuDepartment of Epidemiology and Health Statistics, Public Health College, Qingdao University, Qingdao, China.
Weijing WangDepartment of Epidemiology and Health Statistics, Public Health College, Qingdao University, Qingdao, China.
Wenjie JiangDepartment of Epidemiology and Health Statistics, Public Health College, Qingdao University, Qingdao, China.
Zengchang PangQingdao Municipal Center for Disease Control and Prevention, Qingdao, China.
Dongfeng ZhangDepartment of Epidemiology and Health Statistics, Public Health College, Qingdao University, Qingdao, China.
Qihua TanEpidemiology and Biostatistics, Department of Public Health, University of Southern Denmark, Odense, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous genome-wide association studies on anthropometric measurements have identified more than 100 related loci, but only a small portion of heritability in obesity was explained. Here we present a bivariate twin study to look for the genetic variants associated with body mass index and waist-hip ratio, and to explore the obesity-related pathways in Northern Han Chinese. Cholesky decomposition model for 242 monozygotic and 140 dizygotic twin pairs indicated a moderate genetic correlation (

Indexed as

bivariate genome-wide association studyobesityolfactory transductionsignaling by G protein-coupled receptortwin study

Identifiers

PMID29868124
PMCPMC5964872

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.