ArticleFrontiers in genetics2018
Heterosis Is a Systemic Property Emerging From Non-linear Genotype-Phenotype Relationships: Evidence From
Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 73 citations in OpenAlex.
- Back to the future 2: the implications of germplasm structure on the balance between short- and long-term genetic gain in a changing target population of environments.G3 (Bethesda, Md.) · 2026Article
- Hybrid performance in finger millet (Frontiers in plant science · 2026Article
- GWAS-based population genetic analysis identifies bZIP29 as a heterotic gene in maize.Plant communications · 2025Article
- Formalizing the law of diminishing returns in metabolic networks using an electrical analogy.Royal Society open science · 2024Article
- Fruit Quality Assessment of Novel Hybrid Pummelo × Sweet Orange and Its Molecular Characterization Using Acidity Specific Markers.Food technology and biotechnology · 2024Article
- Sunflower Hybrids and Inbred Lines Adopt Different Physiological Strategies and Proteome Responses to Cope with Water Deficit.Biomolecules · 2023Article
- Heterosis patterns and sources of self-compatibility, cross-compatibility and key nut traits within single and double hybrid crosses of kola [Cola nitida (Vent) Schott and Endl.].Scientific reports · 2023Article
- Large-scale genomic and transcriptomic profiles of rice hybrids reveal a core mechanism underlying heterosis.Genome biology · 2022Article
- The essence of life revisited: how theories can shed light on it.Theory in biosciences = Theorie in den Biowissenschaften · 2022Article
- Heterosis counteracts hybrid breakdown to forestall speciation by parallel natural selection.Proceedings. Biological sciences · 2022Article
- Article
- Review
- Improved redox homeostasis owing to the up-regulation of one-carbon metabolism and related pathways is crucial for yeast heterosis at high temperature.Genome research · 2021Article
- Integrated transcript and metabolite profiling reveals coordination between biomass size and nitrogen metabolism inPlant biotechnology (Tokyo, Japan) · 2021Article
- Comparative Transcriptomic Analysis of Gene Expression Inheritance Patterns Associated with Cabbage Head Heterosis.Plants (Basel, Switzerland) · 2021Article
- Heterosis and Hybrid Crop Breeding: A Multidisciplinary Review.Frontiers in genetics · 2021Review
- Assessment of hybrid vigour, dominance effect and hybrids regeneration potential in the genusHeliyon · 2020Article
- The Pitfalls of Heterosis Coefficients.Plants (Basel, Switzerland) · 2020Article
- Reproductive and productive performance, udder health, and conformation traits of purebred Holstein, F1, and R1 crossbred Holstein × Simmental cows.Tropical animal health and production · 2020Article
- Exploitation of Heterosis in Pearl Millet: A Review.Plants (Basel, Switzerland) · 2020Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heterosis, the superiority of hybrids over their parents for quantitative traits, represents a crucial issue in plant and animal breeding as well as evolutionary biology. Heterosis has given rise to countless genetic, genomic and molecular studies, but has rarely been investigated from the point of view of systems biology. We hypothesized that heterosis is an emergent property of living systems resulting from frequent concave relationships between genotypic variables and phenotypes, or between different phenotypic levels. We chose the enzyme-flux relationship as a model of the concave genotype-phenotype (GP) relationship, and showed that heterosis can be easily created in the laboratory. First, we reconstituted
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.